Version 5.4
Homo sapiens Gene: ENDOU
Summary
InnateDB Gene IDBG-28890.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ENDOU
Gene Name endonuclease, polyU-specific
Synonyms P11; PP11; PRSS26
Species Homo sapiens
Ensembl Gene ENSG00000111405
Encoded Proteins
IDBP-28892
endonuclease, polyU-specific
IDBP-373191
endonuclease, polyU-specific
IDBP-588365
endonuclease, polyU-specific
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a protein with protease activity and is expressed in the placenta. The protein may be useful as a tumor marker. Multiple alternatively spliced transcript variants have been found for this protein. [provided by RefSeq, Feb 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:47709734-47725567
Strand Reverse strand
Band q13.11
Transcripts
ENST00000229003 ENSP00000229003
ENST00000422538 ENSP00000397679
ENST00000545824 ENSP00000445004
ENST00000551186
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0004521 endoribonuclease activity
GO:0005044 scavenger receptor activity
GO:0008083 growth factor activity
GO:0008236 serine-type peptidase activity
GO:0016788 hydrolase activity, acting on ester bonds
GO:0030145 manganese ion binding
GO:0030247 polysaccharide binding
Biological Process
GO:0006508 proteolysis
GO:0006898 receptor-mediated endocytosis
GO:0006955 immune response
GO:0007565 female pregnancy
GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0005886 plasma membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000022468
View Gene Order
ENSBTAG00000012275
Not yet available
Cross-References
SwissProt P21128
TrEMBL B7Z3J4
UniProt Splice Variant
Entrez Gene 8909
UniGene Hs.997
RefSeq NM_001172439 NM_001172440 NM_006025
HUGO HGNC:14369
OMIM 606720
CCDS CCDS53785 CCDS53784 CCDS8754
HPRD 12110
IMGT
EMBL AC004241 AK075446 AK295963 AK300169 AK314688 BC069715 BC074763 BC111782 CH471111 M32402 M36109
GenPept AAA36464 AAA36465 AAH69715 AAH74763 AAI11783 BAG37240 BAG52139 BAH12230 BAH13227 EAW57940
RNA Seq Atlas 8909

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca