Version 5.4
Homo sapiens Gene: COG3
Summary
InnateDB Gene IDBG-29730.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol COG3
Gene Name component of oligomeric golgi complex 3
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000136152
Encoded Proteins
IDBP-29732
component of oligomeric golgi complex 3
IDBP-813192
component of oligomeric golgi complex 3
IDBP-813194
component of oligomeric golgi complex 3
IDBP-813191
component of oligomeric golgi complex 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a component of the conserved oligomeric Golgi (COG) complex which is composed of eight different subunits and is required for normal Golgi morphology and localization. Defects in the COG complex result in multiple deficiencies in protein glycosylation. The protein encoded by this gene is involved in ER-Golgi transport.[provided by RefSeq, Jun 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:45464898-45536630
Strand Forward strand
Band q14.13
Transcripts
ENST00000349995 ENSP00000258654
ENST00000476702 ENSP00000482221
ENST00000465942
ENST00000486940 ENSP00000477882
ENST00000617325
ENST00000617493 ENSP00000481332
ENST00000618913
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 27 experimentally validated interaction(s) in this database.
Experimentally validated
Total 27 [view]
Protein-Protein 27 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008565 protein transporter activity
Biological Process
GO:0006486 protein glycosylation
GO:0006886 intracellular protein transport
GO:0006888 ER to Golgi vesicle-mediated transport
GO:0006890 retrograde vesicle-mediated transport, Golgi to ER
GO:0006891 intra-Golgi vesicle-mediated transport
GO:0033365 protein localization to organelle
GO:0050821 protein stabilization
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005801 cis-Golgi network
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0017119 Golgi transport complex
GO:0032580 Golgi cisterna membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000034893
View Gene Order
ENSBTAG00000017907
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_031431 XM_006719877 XM_006719878
HUGO
OMIM
CCDS CCDS9398
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca