Version 5.4
Homo sapiens Gene: RGL2
Summary
InnateDB Gene IDBG-304189.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RGL2
Gene Name ral guanine nucleotide dissociation stimulator-like 2
Synonyms HKE1.5; KE1.5; RAB2L
Species Homo sapiens
Ensembl Gene ENSG00000237441
Encoded Proteins
IDBP-375530
ral guanine nucleotide dissociation stimulator-like 2
IDBP-473378
ral guanine nucleotide dissociation stimulator-like 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 6:33291654-33299324
Strand Reverse strand
Band p21.32
Transcripts
ENST00000437840
ENST00000425946 ENSP00000392918
ENST00000497454 ENSP00000420211
ENST00000483151
ENST00000491168
ENST00000471319
ENST00000476616
ENST00000478610
ENST00000494550
ENST00000485077
ENST00000460988
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 19 experimentally validated interaction(s) in this database.
Experimentally validated
Total 19 [view]
Protein-Protein 17 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
Biological Process
GO:0007165 signal transduction
GO:0007264 small GTPase mediated signal transduction
GO:0007265 Ras protein signal transduction
GO:0032320 positive regulation of Ras GTPase activity
GO:0043547 positive regulation of GTPase activity
GO:0051056 regulation of small GTPase mediated signal transduction
Cellular Component
GO:0005575 cellular_component
GO:0005622 intracellular
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000041354
View Gene Order
ENSBTAG00000016827
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.509622 Hs.731560
RefSeq NM_001243738 NM_004761
HUGO
OMIM
CCDS CCDS4774
HPRD 03810
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca