Homo sapiens Gene: MFRP
Summary
InnateDB Gene IDBG-307776.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MFRP
Gene Name membrane frizzled-related protein
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000235718
Encoded Proteins
membrane frizzled-related protein
membrane frizzled-related protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the a member of the C1q/tumor necrosis factor superfamily. The encoded protein may be a component of basement membranes and may play a role in cell adhesion. This gene is contained entirely within the 3' UTR of the membrane frizzled-related protein gene on chromosome 11q23 and both genes are expressed from a bicistronic transcript. Mutations in this gene have been associated with late-onset retinal degeneration.[provided by RefSeq, May 2010] This gene encodes a member of the frizzled-related proteins. The encoded protein may play a role in eye development, as mutations in this gene have been associated with nanophthalmos, posterior microphthalmia, retinitis pigmentosa, foveoschisis, and optic disc drusen. The protein is encoded by a bicistronic mRNA, which also encodes C1q and tumor necrosis factor related protein 5.[provided by RefSeq, Feb 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:119341168-119346673
Strand Reverse strand
Band q23.3
Transcripts
ENST00000360167 ENSP00000353291
ENST00000449574 ENSP00000391664
ENST00000529147
ENST00000526059
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0009790 embryo development
Cellular Component
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.632102
RefSeq
HUGO
OMIM
CCDS CCDS8421
HPRD 06941
IMGT
EMBL
GenPept
RNA Seq Atlas