Homo sapiens Gene: TMIE
Summary
InnateDB Gene IDBG-30797.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TMIE
Gene Name transmembrane inner ear
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000181585
Encoded Proteins
transmembrane inner ear
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a transmembrane inner ear protein. Studies in mouse suggest that this gene is required for normal postnatal maturation of sensory hair cells in the cochlea, including correct development of stereocilia bundles. This gene is one of multiple genes responsible for recessive non-syndromic deafness (DFNB), also known as autosomal recessive nonsyndromic hearing loss (ARNSHL), the most common form of congenitally acquired inherited hearing impairment. [provided by RefSeq, Mar 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:46701333-46710886
Strand Forward strand
Band p21.31
Transcripts
ENST00000326431 ENSP00000324775
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0007605 sensory perception of sound
GO:0042472 inner ear morphogenesis
Cellular Component
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Not yet available
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Cross-References
SwissProt Q8NEW7
TrEMBL
UniProt Splice Variant
Entrez Gene 259236
UniGene Hs.185777 Hs.738621
RefSeq NM_147196
HUGO HGNC:30800
OMIM 607237
CCDS CCDS43081
HPRD 06252
IMGT
EMBL AK289625 AY081842 BC126258 BC126260 CH471055
GenPept AAI26259 AAI26261 AAL89820 BAF82314 EAW64781
RNA Seq Atlas 259236