Homo sapiens Gene: CHD2
Summary
InnateDB Gene IDBG-31108.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CHD2
Gene Name chromodomain helicase DNA binding protein 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000173575
Encoded Proteins
chromodomain helicase DNA binding protein 2
chromodomain helicase DNA binding protein 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The CHD family of proteins is characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. CHD genes alter gene expression possibly by modification of chromatin structure thus altering access of the transcriptional apparatus to its chromosomal DNA template. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:92900321-93028003
Strand Forward strand
Band q26.1
Transcripts
ENST00000394196 ENSP00000377747
ENST00000420239 ENSP00000406581
ENST00000557682
ENST00000553829
ENST00000556895
ENST00000554669
ENST00000554894
ENST00000557147
ENST00000554133
ENST00000555227
ENST00000555520
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0001046 core promoter sequence-specific DNA binding
GO:0003677 DNA binding
GO:0004003 ATP-dependent DNA helicase activity
GO:0005524 ATP binding
GO:0042393 histone binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0007517 muscle organ development
GO:0016568 chromatin modification
GO:0032508 DNA duplex unwinding
Cellular Component
GO:0005634 nucleus
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt O14647
TrEMBL G3V418 G3V4S8 Q3YLD5 Q3YLD6 Q6AI05
UniProt Splice Variant
Entrez Gene 1106
UniGene Hs.220864
RefSeq NM_001271 NM_001042572
HUGO HGNC:1917
OMIM 602119
CCDS CCDS10374 CCDS45356
HPRD 03669
IMGT
EMBL AC013394 AF006514 BC007347 BT007050 CH471101 CR627422 CR978407 DQ088985 DQ088986 FJ515838
GenPept AAB87382 AAH07347 AAP35699 AAZ85980 AAZ85981 ACS13730 CAH10509 EAX02160
RNA Seq Atlas 1106