InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: RPL34

Summary

InnateDB Gene

IDBG-33620.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RPL34

Gene Name

ribosomal protein L34

Synonyms

L34

Species

Homo sapiens

Ensembl Gene

ENSG00000109475

Encoded Proteins

IDBP-241135

ribosomal protein L34

IDBP-241137

ribosomal protein L34

IDBP-241139

ribosomal protein L34

IDBP-479392

ribosomal protein L34

IDBP-476836

ribosomal protein L34

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L34E family of ribosomal proteins. It is located in the cytoplasm. This gene originally was thought to be located at 17q21, but it has been mapped to 4q. Transcript variants derived from alternative splicing, alternative transcription initiation sites, and/or alternative polyadenylation exist; these variants encode the same protein. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 4:108620566-108630412

Strand

Forward strand

Band

q25

Transcripts

ENST00000394668	ENSP00000378163
ENST00000394667	ENSP00000378162
ENST00000394665	ENSP00000378160
ENST00000502534	ENSP00000423983
ENST00000503574
ENST00000506397	ENSP00000423316
ENST00000504231

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 21 experimentally validated interaction(s) in this database.

Experimentally validated
Total	21 [view]
Protein-Protein	21 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome

Biological Process

GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0006412	translation
GO:0006413	translational initiation
GO:0006414	translational elongation
GO:0006415	translational termination
GO:0006614	SRP-dependent cotranslational protein targeting to membrane
GO:0010467	gene expression
GO:0016032	viral process
GO:0016070	RNA metabolic process
GO:0016071	mRNA metabolic process
GO:0019058	viral life cycle
GO:0019083	viral transcription
GO:0044267	cellular protein metabolic process

Cellular Component

GO:0005622	intracellular
GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:0070062	extracellular vesicular exosome