Version 5.4
Homo sapiens Gene: DHRS2
Summary
InnateDB Gene IDBG-3407.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DHRS2
Gene Name dehydrogenase/reductase (SDR family) member 2
Synonyms HEP27; SDR25C1
Species Homo sapiens
Ensembl Gene ENSG00000100867
Encoded Proteins
IDBP-3409
dehydrogenase/reductase (SDR family) member 2
IDBP-3411
dehydrogenase/reductase (SDR family) member 2
IDBP-362640
dehydrogenase/reductase (SDR family) member 2
IDBP-599238
dehydrogenase/reductase (SDR family) member 2
IDBP-586312
dehydrogenase/reductase (SDR family) member 2
IDBP-810412
dehydrogenase/reductase (SDR family) member 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 14:23630115-23645639
Strand Forward strand
Band q11.2
Transcripts
ENST00000344777 ENSP00000344674
ENST00000250383 ENSP00000250383
ENST00000432832 ENSP00000401213
ENST00000553896
ENST00000556701
ENST00000556729
ENST00000557535 ENSP00000451895
ENST00000553600 ENSP00000451485
ENST00000556550
ENST00000611765 ENSP00000481607
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004090 carbonyl reductase (NADPH) activity
GO:0016491 oxidoreductase activity
Biological Process
GO:0008152 metabolic process
GO:0008207 C21-steroid hormone metabolic process
GO:0008285 negative regulation of cell proliferation
GO:0009636 response to toxic substance
GO:0034599 cellular response to oxidative stress
GO:0043011 myeloid dendritic cell differentiation
GO:0043066 negative regulation of apoptotic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005634 nucleus
GO:0005635 nuclear envelope
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0070062 extracellular vesicular exosome
Orthologs
No orthologs found for this gene
Cross-References
SwissProt
TrEMBL H0YJG9
UniProt Splice Variant
Entrez Gene 10202
UniGene Hs.272499
RefSeq NM_005794 NM_182908 XM_005267249 XM_006720000 XM_006720001
HUGO HGNC:18349
OMIM 615194
CCDS CCDS41927 CCDS9604
HPRD 07483
IMGT
EMBL AL135999
GenPept
RNA Seq Atlas 10202

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca