Version 5.4
Homo sapiens Gene: NDRG4
Summary
InnateDB Gene IDBG-34297.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NDRG4
Gene Name NDRG family member 4
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000103034
Encoded Proteins
IDBP-34299
NDRG family member 4
IDBP-34305
NDRG family member 4
IDBP-241910
NDRG family member 4
IDBP-241912
NDRG family member 4
IDBP-748400
IDBP-751886
IDBP-747031
IDBP-754042
IDBP-749211
IDBP-745098
IDBP-751299
IDBP-749978
IDBP-747652
IDBP-748781
IDBP-748030
IDBP-746337
IDBP-752199
IDBP-752660
IDBP-745335
IDBP-751019
IDBP-751418
IDBP-748904
IDBP-753357
IDBP-749440
IDBP-751602
IDBP-751082
IDBP-753015
IDBP-751861
IDBP-749203
IDBP-751412
IDBP-749884
IDBP-744922
IDBP-751742
IDBP-751344
IDBP-751408
IDBP-751055
IDBP-747405
IDBP-750764
IDBP-747905
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein that is required for cell cycle progression and survival in primary astrocytes and may be involved in the regulation of mitogenic signalling in vascular smooth muscles cells. Alternative splicing results in multiple transcripts encoding different isoforms.[provided by RefSeq, Jun 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:58462846-58513628
Strand Forward strand
Band q21
Transcripts
ENST00000258187 ENSP00000258187
ENST00000356752 ENSP00000349193
ENST00000394282 ENSP00000377823
ENST00000394279 ENSP00000377820
ENST00000421602
ENST00000568464 ENSP00000454372
ENST00000567454 ENSP00000455054
ENST00000565088 ENSP00000457413
ENST00000566585
ENST00000563317
ENST00000569539 ENSP00000457435
ENST00000561681
ENST00000561779 ENSP00000458092
ENST00000564207 ENSP00000454956
ENST00000568005
ENST00000569578
ENST00000565304 ENSP00000454693
ENST00000566618 ENSP00000456641
ENST00000566041 ENSP00000454767
ENST00000567063 ENSP00000454274
ENST00000565434 ENSP00000456400
ENST00000563978 ENSP00000455541
ENST00000564867 ENSP00000457638
ENST00000561730
ENST00000565981
ENST00000569404 ENSP00000454893
ENST00000562930 ENSP00000455518
ENST00000567667 ENSP00000454509
ENST00000566192 ENSP00000454410
ENST00000568640 ENSP00000456338
ENST00000570248 ENSP00000457659
ENST00000562731 ENSP00000456863
ENST00000561724 ENSP00000456135
ENST00000561720
ENST00000566656 ENSP00000457678
ENST00000565430 ENSP00000455324
ENST00000568999 ENSP00000454745
ENST00000566065
ENST00000563022
ENST00000569026 ENSP00000455421
ENST00000569923 ENSP00000457119
ENST00000562764 ENSP00000455465
ENST00000566265
ENST00000564960
ENST00000569408 ENSP00000454221
ENST00000564486 ENSP00000455660
ENST00000562999 ENSP00000455806
ENST00000563799 ENSP00000458113
ENST00000564126 ENSP00000454216
ENST00000568424 ENSP00000458032
ENST00000562350
ENST00000562725
ENST00000563209
ENST00000561738 ENSP00000454811
ENST00000566061 ENSP00000456583
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0006950 response to stress
GO:0016049 cell growth
GO:0030154 cell differentiation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000036564
View Gene Order
ENSBTAG00000003894
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.322430 Hs.705934 Hs.729314
RefSeq NM_001130487 NM_001242833 NM_001242834 NM_001242835 NM_001242836 NM_020465 NM_022910 XM_006721253 XM_006721256 XM_006721258 XM_006721260 XM_006721261 XM_006721262
HUGO
OMIM
CCDS CCDS10797 CCDS45500 CCDS55999 CCDS58465 CCDS58466 CCDS58467
HPRD 14817
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca