Version 5.4
Homo sapiens Gene: SPAG5
Summary
InnateDB Gene IDBG-36955.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SPAG5
Gene Name sperm associated antigen 5
Synonyms DEEPEST; hMAP126; MAP126
Species Homo sapiens
Ensembl Gene ENSG00000076382
Encoded Proteins
IDBP-36957
sperm associated antigen 5
IDBP-764209
IDBP-594899
sperm associated antigen 5
IDBP-760275
IDBP-761984
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a protein associated with the mitotic spindle apparatus. The encoded protein may be involved in the functional and dynamic regulation of mitotic spindles. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:28577565-28599279
Strand Reverse strand
Band q11.2
Transcripts
ENST00000321765 ENSP00000323300
ENST00000378976 ENSP00000466021
ENST00000536674 ENSP00000444223
ENST00000578479 ENSP00000462663
ENST00000580567 ENSP00000464400
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 31 experimentally validated interaction(s) in this database.
Experimentally validated
Total 31 [view]
Protein-Protein 31 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0000070 mitotic sister chromatid segregation
GO:0007049 cell cycle
GO:0007051 spindle organization
GO:0007059 chromosome segregation
GO:0048015 phosphatidylinositol-mediated signaling
GO:0051301 cell division
GO:0051988 regulation of attachment of spindle microtubules to kinetochore
Cellular Component
GO:0000776 kinetochore
GO:0000777 condensed chromosome kinetochore
GO:0000922 spindle pole
GO:0005737 cytoplasm
GO:0005815 microtubule organizing center
GO:0030496 midbody
GO:0035371 microtubule plus-end
GO:0072686 mitotic spindle
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000002055
View Gene Order
ENSBTAG00000013100
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.514033
RefSeq NM_006461
HUGO
OMIM
CCDS CCDS32594
HPRD 10246
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca