Homo sapiens Gene: GYG2
Summary
InnateDB Gene IDBG-40982.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GYG2
Gene Name glycogenin 2
Synonyms GN-2; GN2;
Species Homo sapiens
Ensembl Gene ENSG00000056998
Encoded Proteins
glycogenin 2
glycogenin 2
glycogenin 2
glycogenin 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the the glycogenin family. Glycogenin is a self-glucosylating protein involved in the initiation reactions of glycogen biosynthesis. A gene on chromosome 3 encodes the muscle glycogenin and this X-linked gene encodes the glycogenin mainly present in liver; both are involved in blood glucose homeostasis. This gene has a short version on chromosome Y, which is 3' truncated and can not make a functional protein. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, May 2010]
This gene encodes a member of the the glycogenin family. Glycogenin is a self-glucosylating protein involved in the initiation reactions of glycogen biosynthesis. A gene on chromosome 3 encodes the muscle glycogenin and this X-linked gene encodes the glycogenin mainly present in liver; both are involved in blood glucose homeostasis. This gene has a short version on chromosome Y, which is 3\' truncated and can not make a functional protein. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, May 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome X:2828788-2882818
Strand Forward strand
Band p22.33
Transcripts
ENST00000381163 ENSP00000370555
ENST00000381161
ENST00000381157 ENSP00000370549
ENST00000353656
ENST00000398806 ENSP00000381786
ENST00000453106
ENST00000520904 ENSP00000430764
ENST00000469234
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
Experimentally validated
Total 10 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008466 glycogenin glucosyltransferase activity
GO:0016757 transferase activity, transferring glycosyl groups
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0005978 glycogen biosynthetic process
GO:0005980 glycogen catabolic process
GO:0006006 glucose metabolic process
GO:0008152 metabolic process
GO:0044281 small molecule metabolic process
Cellular Component
GO:0005829 cytosol
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
Myoclonic epilepsy of Lafora pathway
Glycogen synthesis pathway
Metabolism of carbohydrates pathway
Glycogen breakdown (glycogenolysis) pathway
Metabolism pathway
Disease pathway
Glucose metabolism pathway
Glycogen storage diseases pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.567381 Hs.701629
RefSeq NM_001079855 NM_001184702 NM_001184703 NM_003918 XM_006724521 XM_006724522
HUGO
OMIM
CCDS CCDS14121 CCDS48074
HPRD 02185
IMGT
EMBL
GenPept
RNA Seq Atlas