InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: GYG2

Summary

InnateDB Gene

IDBG-40982.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

GYG2

Gene Name

glycogenin 2

Synonyms

GN-2; GN2

Species

Homo sapiens

Ensembl Gene

ENSG00000056998

Encoded Proteins

IDBP-40984

glycogenin 2

IDBP-40988

glycogenin 2

IDBP-232181

glycogenin 2

IDBP-480658

glycogenin 2

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene encodes a member of the the glycogenin family. Glycogenin is a self-glucosylating protein involved in the initiation reactions of glycogen biosynthesis. A gene on chromosome 3 encodes the muscle glycogenin and this X-linked gene encodes the glycogenin mainly present in liver; both are involved in blood glucose homeostasis. This gene has a short version on chromosome Y, which is 3' truncated and can not make a functional protein. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, May 2010]
This gene encodes a member of the the glycogenin family. Glycogenin is a self-glucosylating protein involved in the initiation reactions of glycogen biosynthesis. A gene on chromosome 3 encodes the muscle glycogenin and this X-linked gene encodes the glycogenin mainly present in liver; both are involved in blood glucose homeostasis. This gene has a short version on chromosome Y, which is 3\' truncated and can not make a functional protein. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, May 2010]

Gene Information

Type

Protein coding

Genomic Location

Chromosome X:2828788-2882818

Strand

Forward strand

Band

p22.33

Transcripts

ENST00000381163	ENSP00000370555
ENST00000381161
ENST00000381157	ENSP00000370549
ENST00000353656
ENST00000398806	ENSP00000381786
ENST00000453106
ENST00000520904	ENSP00000430764
ENST00000469234

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.

Experimentally validated
Total	10 [view]
Protein-Protein	10 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0008466	glycogenin glucosyltransferase activity
GO:0016757	transferase activity, transferring glycosyl groups

Biological Process

GO:0005975	carbohydrate metabolic process
GO:0005978	glycogen biosynthetic process
GO:0005980	glycogen catabolic process
GO:0006006	glucose metabolic process
GO:0008152	metabolic process
GO:0044281	small molecule metabolic process