Version 5.4
Homo sapiens Gene: LCLAT1
Summary
InnateDB Gene IDBG-42337.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LCLAT1
Gene Name lysocardiolipin acyltransferase 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000172954
Encoded Proteins
IDBP-42339
lysocardiolipin acyltransferase 1
IDBP-42341
lysocardiolipin acyltransferase 1
IDBP-42343
lysocardiolipin acyltransferase 1
IDBP-478969
lysocardiolipin acyltransferase 1
IDBP-478596
lysocardiolipin acyltransferase 1
IDBP-482923
lysocardiolipin acyltransferase 1
IDBP-482249
lysocardiolipin acyltransferase 1
IDBP-476427
lysocardiolipin acyltransferase 1
IDBP-474148
lysocardiolipin acyltransferase 1
IDBP-480558
lysocardiolipin acyltransferase 1
IDBP-476610
lysocardiolipin acyltransferase 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 2:30447226-30644225
Strand Forward strand
Band p23.1
Transcripts
ENST00000319406 ENSP00000368826
ENST00000379509 ENSP00000368823
ENST00000309052 ENSP00000310551
ENST00000466477 ENSP00000419966
ENST00000465200 ENSP00000420481
ENST00000491680
ENST00000488144 ENSP00000417951
ENST00000465538 ENSP00000417565
ENST00000478015 ENSP00000419735
ENST00000476038 ENSP00000419646
ENST00000497423 ENSP00000417875
ENST00000476535 ENSP00000419444
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity
GO:0016746 transferase activity, transferring acyl groups
Biological Process
GO:0006644 phospholipid metabolic process
GO:0006654 phosphatidic acid biosynthetic process
GO:0007275 multicellular organismal development
GO:0008152 metabolic process
GO:0016024 CDP-diacylglycerol biosynthetic process
GO:0019432 triglyceride biosynthetic process
GO:0035965 cardiolipin acyl-chain remodeling
GO:0044255 cellular lipid metabolic process
GO:0044281 small molecule metabolic process
GO:0046474 glycerophospholipid biosynthetic process
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000054469
View Gene Order
ENSBTAG00000005014
Not yet available
Pathways
NETPATH
REACTOME
REACT_120906
Synthesis of PA pathway
REACT_121006
Acyl chain remodeling of CL pathway
REACT_1190
Triglyceride Biosynthesis pathway
REACT_22279
Fatty acid, triacylglycerol, and ketone body metabolism pathway
REACT_22258
Metabolism of lipids and lipoproteins pathway
REACT_121401
Glycerophospholipid biosynthesis pathway
REACT_120870
Phospholipid metabolism pathway
REACT_111217
Metabolism pathway
KEGG
hsa00564
Glycerophospholipid metabolism pathway
hsa00561
Glycerolipid metabolism pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.468048 Hs.625116 Hs.662770
RefSeq NM_001002257 NM_182551 XM_005264244 XM_005264245 XM_006711981
HUGO
OMIM
CCDS CCDS1772 CCDS42670
HPRD 17458
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca