Version 5.4
Homo sapiens Gene: EHD3
Summary
InnateDB Gene IDBG-42688.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol EHD3
Gene Name EH-domain containing 3
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000013016
Encoded Proteins
IDBP-42692
EH-domain containing 3
IDBP-602698
EH-domain containing 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 2:31234337-31269447
Strand Forward strand
Band p23.1
Transcripts
ENST00000322054 ENSP00000327116
ENST00000541626 ENSP00000440685
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 8 [view]
Protein-Protein 6 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003924 GTPase activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0005525 GTP binding
Biological Process
GO:0006184 GTP catabolic process
GO:0007596 blood coagulation
GO:0032456 endocytic recycling
GO:0051260 protein homooligomerization
GO:0072661 protein targeting to plasma membrane
GO:0086036 regulation of cardiac muscle cell membrane potential
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0010008 endosome membrane
GO:0030139 endocytic vesicle
GO:0048471 perinuclear region of cytoplasm
GO:0055038 recycling endosome membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000024065
View Gene Order
ENSBTAG00000001662
Not yet available
Pathways
NETPATH
REACTOME
REACT_24970
Factors involved in megakaryocyte development and platelet production pathway
REACT_604
Hemostasis pathway
KEGG
hsa04144
Endocytosis pathway
INOH
PID NCI
Cross-References
SwissProt Q9NZN3
TrEMBL
UniProt Splice Variant
Entrez Gene 30845
UniGene Hs.368808 Hs.604749 Hs.605056 Hs.724055 Hs.726971
RefSeq NM_014600
HUGO HGNC:3244
OMIM 605891
CCDS CCDS1774
HPRD
IMGT
EMBL AF181264 AF214736 AL121657 CH471053
GenPept AAF32285 AAF40471 EAX00480 EAX00481
RNA Seq Atlas 30845

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca