InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: PTN

Summary

InnateDB Gene

IDBG-42963.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PTN

Gene Name

pleiotrophin

Synonyms

HARP; HBGF8; HBNF; NEGF1

Species

Homo sapiens

Ensembl Gene

ENSG00000105894

Encoded Proteins

IDBP-42965

pleiotrophin

IDBP-244342

pleiotrophin

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.

Gene Information

Type

Protein coding

Genomic Location

Chromosome 7:137227341-137343865

Strand

Reverse strand

Band

q33

Transcripts

ENST00000348225	ENSP00000341170
ENST00000393083	ENSP00000376798

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 116 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	116 [view]
Protein-Protein	114 [view]
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004864	protein phosphatase inhibitor activity
GO:0008083	growth factor activity
GO:0008201	heparin binding

Biological Process

GO:0001503	ossification
GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway
GO:0007399	nervous system development
GO:0007612	learning
GO:0008284	positive regulation of cell proliferation
GO:0030282	bone mineralization
GO:0043086	negative regulation of catalytic activity
GO:0051781	positive regulation of cell division

Cellular Component

GO:0005615	extracellular space
GO:0005783	endoplasmic reticulum

Orthologs

Species

Mus musculus

Bos taurus

Gene ID

Gene Order

ENSMUSG00000029838

View Gene Order

ENSBTAG00000002317

Not yet available

Pathways

NETPATH

REACTOME

KEGG

INOH

PID NCI

syndecan_3_pathway

Syndecan-3-mediated signaling events

Cross-References

SwissProt

P21246

TrEMBL

A0A024R778 C9JR52

UniProt Splice Variant

Entrez Gene

5764

UniGene

Hs.371249 Hs.597821 Hs.713732

RefSeq

NM_002825 XM_005250515 XM_005250516

HUGO

HGNC:9630

OMIM

162095

CCDS

CCDS5844

HPRD

IMGT

EMBL

AB004306 AC018728 AC078842 AK290488 AK313424 BC005916 BT019692 CH236950 CH471070 CR450338 D90226 M57399 S50394 S50405 S50408 S50409 S59641 S60110 S60111 S60736 X52946

GenPept

AAA35961 AAB24425 AAB26456 AAH05916 AAV38498 BAA14261 BAA22944 BAF83177 BAG36216 CAA37121 CAG29334 EAL24052 EAW83869 EAW83872

RNA Seq Atlas

5764