Homo sapiens Gene: PTN
Summary
InnateDB Gene IDBG-42963.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PTN
Gene Name pleiotrophin
Synonyms HARP; HBGF8; HBNF; NEGF1;
Species Homo sapiens
Ensembl Gene ENSG00000105894
Encoded Proteins
pleiotrophin
pleiotrophin
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 7:137227341-137343865
Strand Reverse strand
Band q33
Transcripts
ENST00000348225 ENSP00000341170
ENST00000393083 ENSP00000376798
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 116 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 116 [view]
Protein-Protein 114 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004864 protein phosphatase inhibitor activity
GO:0008083 growth factor activity
GO:0008201 heparin binding
Biological Process
GO:0001503 ossification
GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway
GO:0007399 nervous system development
GO:0007612 learning
GO:0008284 positive regulation of cell proliferation
GO:0030282 bone mineralization
GO:0043086 negative regulation of catalytic activity
GO:0051781 positive regulation of cell division
Cellular Component
GO:0005615 extracellular space
GO:0005783 endoplasmic reticulum
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
KEGG
INOH
PID BIOCARTA
PID NCI
Syndecan-3-mediated signaling events
Cross-References
SwissProt P21246
TrEMBL A0A024R778 C9JR52
UniProt Splice Variant
Entrez Gene 5764
UniGene Hs.371249 Hs.597821 Hs.713732
RefSeq NM_002825 XM_005250515 XM_005250516
HUGO HGNC:9630
OMIM 162095
CCDS CCDS5844
HPRD
IMGT
EMBL AB004306 AC018728 AC078842 AK290488 AK313424 BC005916 BT019692 CH236950 CH471070 CR450338 D90226 M57399 S50394 S50405 S50408 S50409 S59641 S60110 S60111 S60736 X52946
GenPept AAA35961 AAB24425 AAB26456 AAH05916 AAV38498 BAA14261 BAA22944 BAF83177 BAG36216 CAA37121 CAG29334 EAL24052 EAW83869 EAW83872
RNA Seq Atlas 5764