Homo sapiens Gene: PPID
Summary
InnateDB Gene IDBG-43002.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PPID
Gene Name peptidylprolyl isomerase D
Synonyms CYP-40; CYPD;
Species Homo sapiens
Ensembl Gene ENSG00000171497
Encoded Proteins
peptidylprolyl isomerase D
peptidylprolyl isomerase D
peptidylprolyl isomerase D
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein has been shown to possess PPIase activity and, similar to other family members, can bind to the immunosuppressant cyclosporin A. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:158709134-158723396
Strand Reverse strand
Band q32.1
Transcripts
ENST00000307720 ENSP00000303754
ENST00000512699 ENSP00000423207
ENST00000507213 ENSP00000421221
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 58 experimentally validated interaction(s) in this database.
Experimentally validated
Total 58 [view]
Protein-Protein 58 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003755 peptidyl-prolyl cis-trans isomerase activity
GO:0005515 protein binding
GO:0008134 transcription factor binding
GO:0016018 cyclosporin A binding
GO:0030331 estrogen receptor binding
GO:0030544 Hsp70 protein binding
GO:0031072 heat shock protein binding
GO:0051879 Hsp90 protein binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0000413 protein peptidyl-prolyl isomerization
GO:0006457 protein folding
GO:0006461 protein complex assembly
GO:0006915 apoptotic process
GO:0015031 protein transport
GO:0019076 viral release from host cell
GO:0034389 lipid particle organization
GO:0043065 positive regulation of apoptotic process
GO:0045070 positive regulation of viral genome replication
GO:0050714 positive regulation of protein secretion
GO:0061077 chaperone-mediated protein folding
GO:0071492 cellular response to UV-A
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Not yet available
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Pathways
NETPATH
REACTOME
KEGG
INOH
PID BIOCARTA
PID NCI
C-MYB transcription factor network
Cross-References
SwissProt Q08752
TrEMBL E5KN55 H0Y8J0
UniProt Splice Variant
Entrez Gene 5481
UniGene Hs.183958
RefSeq NM_005038
HUGO HGNC:9257
OMIM 601753
CCDS CCDS3801
HPRD
IMGT
EMBL AC107219 AK313929 AY714221 BC030707 CH471056 D63861 HQ205146 HQ205147 HQ205148 HQ205149 HQ205151 HQ205152 HQ205153 HQ205154 HQ205155 HQ205156 HQ205157 HQ205158 HQ205159 HQ205160 HQ205161 HQ205162 HQ205163 HQ205165 HQ205166 HQ205168 HQ205169 HQ205170 HQ205171 HQ205172 HQ205173 HQ205174 HQ205175 HQ205176 HQ205177 HQ205178 HQ205179 HQ205180 HQ205181 HQ205182 HQ205183 HQ205184 HQ205185 L11667
GenPept AAA35731 AAH30707 AAT97986 ADP90614 ADP90615 ADP90616 ADP90617 ADP90619 ADP90620 ADP90621 ADP90622 ADP90623 ADP90624 ADP90625 ADP90626 ADP90627 ADP90628 ADP90629 ADP90630 ADP90631 ADP90633 ADP90634 ADP90636 ADP90637 ADP90638 ADP90639 ADP90640 ADP90641 ADP90642 ADP90643 ADP90644 ADP90645 ADP90646 ADP90647 ADP90648 ADP90649 ADP90650 ADP90651 ADP90652 ADP90653 BAA09923 BAG36649 EAX04853
RNA Seq Atlas 5481