Homo sapiens Gene: SERPINB2
Summary
InnateDB Gene IDBG-4558.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SERPINB2
Gene Name serpin peptidase inhibitor, clade B (ovalbumin), member 2
Synonyms HsT1201; PAI; PAI-2; PAI2; PLANH2;
Species Homo sapiens
Ensembl Gene ENSG00000197632
Encoded Proteins
serpin peptidase inhibitor, clade B (ovalbumin), member 2
serpin peptidase inhibitor, clade B (ovalbumin), member 2
serpin peptidase inhibitor, clade B (ovalbumin), member 2
serpin peptidase inhibitor, clade B (ovalbumin), member 2
serpin peptidase inhibitor, clade B (ovalbumin), member 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation from Orthologs
Summary
[Mus musculus] LPS stimulation promotes the formation of CEBPB complexes on the Serpinb2 promoter to drive transcription.
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 18:63871692-63903890
Strand Forward strand
Band q21.33
Transcripts
ENST00000299502 ENSP00000299502
ENST00000404622 ENSP00000385397
ENST00000457692 ENSP00000401645
ENST00000413956 ENSP00000402386
ENST00000443281 ENSP00000397096
ENST00000482254
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 10 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004867 serine-type endopeptidase inhibitor activity
Biological Process
GO:0007596 blood coagulation
GO:0010951 negative regulation of endopeptidase activity
GO:0030162 regulation of proteolysis
GO:0042060 wound healing
GO:0042730 fibrinolysis
GO:0043066 negative regulation of apoptotic process
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0005886 plasma membrane
Orthologs
Species
Mus musculus
Gene ID
Gene Order
Method
Confidence
Comments
Low
Tentative data, uncurated. RBBH derived.
Pathways
NETPATH
REACTOME
Dissolution of Fibrin Clot pathway
Hemostasis pathway
KEGG
Amoebiasis pathway
INOH
PID BIOCARTA
Fibrinolysis pathway [Biocarta view]
PID NCI
Cross-References
SwissProt P05120
TrEMBL E7EPJ9 E7ERB5 E9PDK7 Q6LDR6
UniProt Splice Variant
Entrez Gene 5055
UniGene Hs.594481 Hs.644669
RefSeq NM_001143818 NM_002575
HUGO HGNC:8584
OMIM 173390
CCDS CCDS11989
HPRD
IMGT
EMBL AC072051 BC012609 J02685 J03603 M18082 M23092 M24651 M24652 M24653 M24654 M24655 M24656 M24657 M31547 M31548 M31549 M31550 M31551 Y00630
GenPept AAA36413 AAA36797 AAA60004 AAA60005 AAA60006 AAA60348 AAH12609 CAA68666
RNA Seq Atlas 5055