Version 5.4
Homo sapiens Gene: SERPINB2
Summary
InnateDB Gene IDBG-4558.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SERPINB2
Gene Name serpin peptidase inhibitor, clade B (ovalbumin), member 2
Synonyms HsT1201; PAI; PAI-2; PAI2; PLANH2
Species Homo sapiens
Ensembl Gene ENSG00000197632
Encoded Proteins
IDBP-4560
serpin peptidase inhibitor, clade B (ovalbumin), member 2
IDBP-294281
serpin peptidase inhibitor, clade B (ovalbumin), member 2
IDBP-372020
serpin peptidase inhibitor, clade B (ovalbumin), member 2
IDBP-372023
serpin peptidase inhibitor, clade B (ovalbumin), member 2
IDBP-372027
serpin peptidase inhibitor, clade B (ovalbumin), member 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation from Orthologs
Summary
PMID 23472114
[Mus musculus] LPS stimulation promotes the formation of CEBPB complexes on the Serpinb2 promoter to drive transcription.
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 18:63871692-63903890
Strand Forward strand
Band q21.33
Transcripts
ENST00000299502 ENSP00000299502
ENST00000404622 ENSP00000385397
ENST00000457692 ENSP00000401645
ENST00000413956 ENSP00000402386
ENST00000443281 ENSP00000397096
ENST00000482254
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 10 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004867 serine-type endopeptidase inhibitor activity
Biological Process
GO:0007596 blood coagulation
GO:0010951 negative regulation of endopeptidase activity
GO:0030162 regulation of proteolysis
GO:0042060 wound healing
GO:0042730 fibrinolysis
GO:0043066 negative regulation of apoptotic process
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0005886 plasma membrane
Orthologs
Species
Mus musculus
Gene ID
Gene Order
ENSMUSG00000062345
View Gene Order
Pathways
NETPATH
REACTOME
REACT_641
Dissolution of Fibrin Clot pathway
REACT_604
Hemostasis pathway
KEGG
hsa05146
Amoebiasis pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.594481 Hs.644669
RefSeq NM_001143818 NM_002575
HUGO
OMIM
CCDS CCDS11989
HPRD 01420
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca