Version 5.4
Homo sapiens Gene: MAP1LC3B
Summary
InnateDB Gene IDBG-45638.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MAP1LC3B
Gene Name microtubule-associated protein 1 light chain 3 beta
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000140941
Encoded Proteins
IDBP-45640
microtubule-associated protein 1 light chain 3 beta
IDBP-753381
IDBP-750995
IDBP-749512
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The product of this gene is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. Studies on the rat homolog implicate a role for this gene in autophagy, a process that involves the bulk degradation of cytoplasmic component. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:87383995-87404779
Strand Forward strand
Band q24.2
Transcripts
ENST00000268607 ENSP00000268607
ENST00000563720
ENST00000564638
ENST00000562778
ENST00000599768
ENST00000570189 ENSP00000457141
ENST00000565788 ENSP00000457225
ENST00000561823
ENST00000564844 ENSP00000454293
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 154 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 154 [view]
Protein-Protein 152 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0000045 autophagic vacuole assembly
GO:0006914 autophagy
Cellular Component
GO:0000421 autophagic vacuole membrane
GO:0005622 intracellular
GO:0005737 cytoplasm
GO:0005776 autophagic vacuole
GO:0005874 microtubule
GO:0005930 axoneme
GO:0012505 endomembrane system
GO:0031090 organelle membrane
GO:0031410 cytoplasmic vesicle
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000031812
View Gene Order
ENSBTAG00000011632
Not yet available
Cross-References
SwissProt
TrEMBL H3BM99
UniProt Splice Variant
Entrez Gene 81631
UniGene Hs.356061 Hs.569691 Hs.717559
RefSeq NM_022818 XM_005256184
HUGO HGNC:13352
OMIM 609604
CCDS CCDS10960
HPRD 14358
IMGT
EMBL AC010531
GenPept
RNA Seq Atlas 81631

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca