Version 5.4
Homo sapiens Gene: CAND1
Summary
InnateDB Gene IDBG-45753.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CAND1
Gene Name cullin-associated and neddylation-dissociated 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000111530
Encoded Proteins
IDBP-590682
cullin-associated and neddylation-dissociated 1
IDBP-585728
cullin-associated and neddylation-dissociated 1
IDBP-592676
cullin-associated and neddylation-dissociated 1
IDBP-592579
cullin-associated and neddylation-dissociated 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 12:67269281-67319951
Strand Forward strand
Band q14.3
Transcripts
ENST00000545606 ENSP00000442318
ENST00000541058
ENST00000539109
ENST00000539434
ENST00000540525 ENSP00000437594
ENST00000535146
ENST00000540319 ENSP00000445794
ENST00000544619 ENSP00000444089
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 661 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 661 [view]
Protein-Protein 661 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005488 binding
GO:0005515 protein binding
GO:0017025 TBP-class protein binding
Biological Process
GO:0010265 SCF complex assembly
GO:0016567 protein ubiquitination
GO:0030154 cell differentiation
GO:0043086 negative regulation of catalytic activity
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly
Cellular Component
GO:0000151 ubiquitin ligase complex
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0016020 membrane
GO:0031461 cullin-RING ubiquitin ligase complex
GO:0043231 intracellular membrane-bounded organelle
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000020114
View Gene Order
ENSBTAG00000009939
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.505983 Hs.546407 Hs.603256 Hs.623675 Hs.633838 Hs.703396
RefSeq NM_018448
HUGO
OMIM
CCDS CCDS8977
HPRD 06983
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca