Homo sapiens Gene: CAND1
Summary
InnateDB Gene IDBG-45753.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CAND1
Gene Name cullin-associated and neddylation-dissociated 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000111530
Encoded Proteins
cullin-associated and neddylation-dissociated 1
cullin-associated and neddylation-dissociated 1
cullin-associated and neddylation-dissociated 1
cullin-associated and neddylation-dissociated 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 12:67269281-67319951
Strand Forward strand
Band q14.3
Transcripts
ENST00000545606 ENSP00000442318
ENST00000541058
ENST00000539109
ENST00000539434
ENST00000540525 ENSP00000437594
ENST00000535146
ENST00000540319 ENSP00000445794
ENST00000544619 ENSP00000444089
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 661 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 661 [view]
Protein-Protein 661 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005488 binding
GO:0005515 protein binding
GO:0017025 TBP-class protein binding
Biological Process
GO:0010265 SCF complex assembly
GO:0016567 protein ubiquitination
GO:0030154 cell differentiation
GO:0043086 negative regulation of catalytic activity
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly
Cellular Component
GO:0000151 ubiquitin ligase complex
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0016020 membrane
GO:0031461 cullin-RING ubiquitin ligase complex
GO:0043231 intracellular membrane-bounded organelle
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt Q86VP6
TrEMBL B3KMG3 F5H6I6
UniProt Splice Variant
Entrez Gene 55832
UniGene Hs.505983 Hs.546407 Hs.603256 Hs.623675 Hs.633838 Hs.703396
RefSeq NM_018448
HUGO HGNC:30688
OMIM 607727
CCDS CCDS8977
HPRD 06983
IMGT
EMBL AB020636 AC012518 AC078983 AF157326 AK001791 AK027404 AK027783 AK314358 AL133560 AL136810 AL833880 BC004232 BC026220 BC050341 CH471054
GenPept AAF67492 AAH04232 AAH26220 AAH50341 BAA74852 BAB55090 BAB55365 BAG36990 BAG50975 CAB63714 CAB66744 CAD38737 EAW97172
RNA Seq Atlas 55832