Homo sapiens Gene: STARD3
Summary
InnateDB Gene IDBG-45854.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol STARD3
Gene Name StAR-related lipid transfer (START) domain containing 3
Synonyms CAB1; es64; MLN64;
Species Homo sapiens
Ensembl Gene ENSG00000131748
Encoded Proteins
StAR-related lipid transfer (START) domain containing 3
StAR-related lipid transfer (START) domain containing 3
StAR-related lipid transfer (START) domain containing 3
StAR-related lipid transfer (START) domain containing 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of a subfamily of lipid trafficking proteins that are characterized by a C-terminal steroidogenic acute regulatory domain and an N-terminal metastatic lymph node 64 domain. The encoded protein localizes to the membranes of late endosomes and may be involved in exporting cholesterol. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Oct 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:39637065-39663484
Strand Forward strand
Band q12
Transcripts
ENST00000336308 ENSP00000337446
ENST00000394250 ENSP00000377794
ENST00000443521 ENSP00000411710
ENST00000488876
ENST00000484773
ENST00000460894
ENST00000481171
ENST00000471896
ENST00000544210 ENSP00000439869
ENST00000580331 ENSP00000462541
ENST00000583884 ENSP00000464288
ENST00000585214
ENST00000580551
ENST00000583582
ENST00000580611 ENSP00000463613
ENST00000583718 ENSP00000464204
ENST00000582874
ENST00000578384
ENST00000583419 ENSP00000463681
ENST00000578577 ENSP00000464472
ENST00000578686
ENST00000577248 ENSP00000463460
ENST00000579479 ENSP00000462483
ENST00000578232
ENST00000578254
ENST00000585269
ENST00000584850
ENST00000581894 ENSP00000462859
ENST00000583639
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008289 lipid binding
GO:0015485 cholesterol binding
GO:0017127 cholesterol transporter activity
Biological Process
GO:0006629 lipid metabolic process
GO:0006694 steroid biosynthetic process
GO:0006701 progesterone biosynthetic process
GO:0006839 mitochondrial transport
GO:0008202 steroid metabolic process
GO:0008203 cholesterol metabolic process
GO:0030301 cholesterol transport
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005765 lysosomal membrane
GO:0005768 endosome
GO:0016021 integral component of membrane
GO:0031902 late endosome membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt
TrEMBL J3KSH0 J3KSL3 J3KT87 J3QRG8
UniProt Splice Variant
Entrez Gene 10948
UniGene Hs.728838
RefSeq NM_001165937 NM_001165938 NM_006804 XM_006721645
HUGO HGNC:17579
OMIM 607048
CCDS CCDS11341 CCDS54117 CCDS54118
HPRD 06132
IMGT
EMBL AC087491
GenPept
RNA Seq Atlas 10948