InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: SRP54

Summary

InnateDB Gene

IDBG-4659.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SRP54

Gene Name

signal recognition particle 54kDa

Synonyms

Species

Homo sapiens

Ensembl Gene

ENSG00000100883

Encoded Proteins

IDBP-4661

signal recognition particle 54kDa

IDBP-591532

signal recognition particle 54kDa

IDBP-599411

signal recognition particle 54kDa

IDBP-583166

signal recognition particle 54kDa

IDBP-603512

signal recognition particle 54kDa

IDBP-583986

signal recognition particle 54kDa

IDBP-586899

signal recognition particle 54kDa

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.

Gene Information

Type

Protein coding

Genomic Location

Chromosome 14:34981957-35029567

Strand

Forward strand

Band

q13.2

Transcripts

ENST00000216774	ENSP00000216774
ENST00000556994	ENSP00000451818
ENST00000554803	ENSP00000451037
ENST00000555746	ENSP00000451647
ENST00000553544
ENST00000555317
ENST00000555557	ENSP00000451775
ENST00000556380	ENSP00000451313
ENST00000555535
ENST00000553923
ENST00000556445
ENST00000556992
ENST00000546080	ENSP00000440629

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 29 experimentally validated interaction(s) in this database.

Experimentally validated
Total	29 [view]
Protein-Protein	26 [view]
Protein-DNA	3 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003924	GTPase activity
GO:0005525	GTP binding
GO:0008144	drug binding
GO:0008312	7S RNA binding
GO:0019003	GDP binding
GO:0030942	endoplasmic reticulum signal peptide binding
GO:0043021	ribonucleoprotein complex binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0006184	GTP catabolic process
GO:0006412	translation
GO:0006614	SRP-dependent cotranslational protein targeting to membrane
GO:0006616	SRP-dependent cotranslational protein targeting to membrane, translocation
GO:0006617	SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition
GO:0010467	gene expression
GO:0042493	response to drug
GO:0044267	cellular protein metabolic process
GO:0045047	protein targeting to ER

Cellular Component

GO:0005634	nucleus
GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0005786	signal recognition particle, endoplasmic reticulum targeting
GO:0005829	cytosol
GO:0016607	nuclear speck
GO:0048500	signal recognition particle

Orthologs

Species

Mus musculus

Bos taurus

Gene ID

Gene Order

ENSMUSG00000073079

View Gene Order

ENSBTAG00000019085

Not yet available

Pathways

NETPATH

REACTOME

REACT_115902

SRP-dependent cotranslational protein targeting to membrane pathway

REACT_1014

Translation pathway

REACT_17015

Metabolism of proteins pathway

REACT_71

Gene Expression pathway

KEGG

hsa03060

Protein export pathway

INOH

PID NCI

Cross-References

SwissProt

P61011

TrEMBL

G3V346 G3V480 G3V4F7

UniProt Splice Variant

Entrez Gene

6729

UniGene

Hs.167535 Hs.702481

RefSeq

NM_001146282 NM_003136

HUGO

HGNC:11301

OMIM

604857

CCDS

CCDS9652 CCDS53893

HPRD

05330

IMGT

EMBL

AK300824 AK312853 AL049776 BC000652 BC003389 U51920 X86373

GenPept

AAC50994 AAH00652 AAH03389 BAG35706 BAG62478 CAA60132

RNA Seq Atlas

6729