Version 5.4
Homo sapiens Gene: PDIA4
Summary
InnateDB Gene IDBG-47155.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PDIA4
Gene Name protein disulfide isomerase family A, member 4
Synonyms ERp-72; ERP70; ERP72
Species Homo sapiens
Ensembl Gene ENSG00000155660
Encoded Proteins
IDBP-47157
protein disulfide isomerase family A, member 4
IDBP-387209
protein disulfide isomerase family A, member 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 7:149003062-149028641
Strand Reverse strand
Band q36.1
Transcripts
ENST00000286091 ENSP00000286091
ENST00000413966 ENSP00000408628
ENST00000466592
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 63 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 63 [view]
Protein-Protein 63 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003756 protein disulfide isomerase activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0016853 isomerase activity
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006457 protein folding
GO:0009306 protein secretion
GO:0034976 response to endoplasmic reticulum stress
GO:0045454 cell redox homeostasis
GO:0061077 chaperone-mediated protein folding
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005788 endoplasmic reticulum lumen
GO:0009986 cell surface
GO:0042470 melanosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000025823
View Gene Order
ENSBTAG00000017143
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa05110
Vibrio cholerae infection pathway
hsa04141
Protein processing in endoplasmic reticulum pathway
INOH
PID NCI
Cross-References
SwissProt P13667
TrEMBL C9JMN9
UniProt Splice Variant
Entrez Gene 9601
UniGene Hs.593793 Hs.93659
RefSeq NM_004911 XM_006716185
HUGO HGNC:30167
OMIM
CCDS CCDS5893
HPRD
IMGT
EMBL AC093743 AK290971 BC000425 BC001928 BC006344 BC011754 CH471146 J05016
GenPept AAA58460 AAH00425 AAH01928 AAH06344 AAH11754 AAQ96863 BAF83660 EAW80065 EAW80066
RNA Seq Atlas 9601

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca