Homo sapiens Gene: GLYAT
Summary
InnateDB Gene IDBG-47902.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GLYAT
Gene Name glycine-N-acyltransferase
Synonyms ACGNAT; CAT; GAT;
Species Homo sapiens
Ensembl Gene ENSG00000149124
Encoded Proteins
glycine-N-acyltransferase
glycine-N-acyltransferase
glycine-N-acyltransferase
glycine-N-acyltransferase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The glycine-N-acyltransferase protein conjugates glycine with acyl-CoA substrates in the mitochondria. The protein is thought to be important in the detoxification of endogenous and xenobiotic acyl-CoA's. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
The glycine-N-acyltransferase protein conjugates glycine with acyl-CoA substrates in the mitochondria. The protein is thought to be important in the detoxification of endogenous and xenobiotic acyl-CoA\'s. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:58640426-58731974
Strand Reverse strand
Band q12.1
Transcripts
ENST00000344743 ENSP00000340200
ENST00000278400 ENSP00000278400
ENST00000529732 ENSP00000431688
ENST00000531084
ENST00000586098 ENSP00000468512
ENST00000611865 ENSP00000484592
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 3 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0016746 transferase activity, transferring acyl groups
GO:0047961 glycine N-acyltransferase activity
GO:0047962 glycine N-benzoyltransferase activity
Biological Process
GO:0006544 glycine metabolic process
GO:0006637 acyl-CoA metabolic process
GO:0006805 xenobiotic metabolic process
GO:0009636 response to toxic substance
GO:0032787 monocarboxylic acid metabolic process
GO:0044281 small molecule metabolic process
Cellular Component
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Gene ID
Gene Order
Method
Confidence
Comments
Low
Tentative data, uncurated. RBBH derived.
Pathways
NETPATH
REACTOME
Amino Acid conjugation pathway
Phase II conjugation pathway
Conjugation of carboxylic acids pathway
Metabolism pathway
Biological oxidations pathway
Conjugation of salicylate with glycine pathway
Conjugation of benzoate with glycine pathway
KEGG
Phenylalanine metabolism pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt Q6IB77
TrEMBL
UniProt Splice Variant
Entrez Gene 10249
UniGene Hs.145384
RefSeq NM_005838 NM_201648
HUGO HGNC:13734
OMIM 607424
CCDS CCDS7970 CCDS7971
HPRD
IMGT
EMBL AB013093 AF023466 AP000445 BC009785 CR456927
GenPept AAB81453 AAH09785 CAG33208
RNA Seq Atlas 10249