Homo sapiens Gene: LGALS7
Summary
InnateDB Gene IDBG-49458.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LGALS7
Gene Name lectin, galactoside-binding, soluble, 7
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000205076
Encoded Proteins
lectin, galactoside-binding, soluble, 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Differential and in situ hybridization studies indicate that this lectin is specifically expressed in keratinocytes and found mainly in stratified squamous epithelium. A duplicate copy of this gene (GeneID:3963) is found adjacent to, but on the opposite strand on chromosome 19. [provided by RefSeq, Jul 2008] The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Differential and in situ hybridization studies indicate that this lectin is specifically expressed in keratinocytes and found mainly in stratified squamous epithelium. A duplicate copy of this gene (GeneID:653499) is found adjacent to, but on the opposite strand on chromosome 19. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:38770971-38773492
Strand Reverse strand
Band q13.2
Transcripts
ENST00000378626 ENSP00000367891
ENST00000599035 ENSP00000472380
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.
Experimentally validated
Total 15 [view]
Protein-Protein 15 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0030246 carbohydrate binding
Biological Process
GO:0006915 apoptotic process
GO:0007157 heterophilic cell-cell adhesion
Cellular Component
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0070062 extracellular vesicular exosome
Orthologs
No orthologs found for this gene
Cross-References
SwissProt
TrEMBL M0R281
UniProt Splice Variant
Entrez Gene 653499
UniGene
RefSeq NM_002307
HUGO HGNC:6568
OMIM 600615
CCDS CCDS33012
HPRD 09002
IMGT
EMBL AC022144
GenPept
RNA Seq Atlas 3963 653499