Version 5.4
Homo sapiens Gene: SLC1A4
Summary
InnateDB Gene IDBG-54041.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC1A4
Gene Name solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
Synonyms ASCT1; SATT
Species Homo sapiens
Ensembl Gene ENSG00000115902
Encoded Proteins
IDBP-54043
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
IDBP-597618
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 2:64988477-65023865
Strand Forward strand
Band p14
Transcripts
ENST00000234256 ENSP00000234256
ENST00000493121
ENST00000471551
ENST00000480594
ENST00000531327 ENSP00000431942
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 1 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005254 chloride channel activity
GO:0015175 neutral amino acid transmembrane transporter activity
GO:0015180 L-alanine transmembrane transporter activity
GO:0015184 L-cystine transmembrane transporter activity
GO:0015186 L-glutamine transmembrane transporter activity
GO:0015193 L-proline transmembrane transporter activity
GO:0015194 L-serine transmembrane transporter activity
GO:0015195 L-threonine transmembrane transporter activity
GO:0017153 sodium:dicarboxylate symporter activity
GO:0034590 L-hydroxyproline transmembrane transporter activity
Biological Process
GO:0006811 ion transport
GO:0006821 chloride transport
GO:0006835 dicarboxylic acid transport
GO:0006865 amino acid transport
GO:0006868 glutamine transport
GO:0015808 L-alanine transport
GO:0015811 L-cystine transport
GO:0015824 proline transport
GO:0015825 L-serine transport
GO:0015826 threonine transport
GO:0034589 hydroxyproline transport
GO:0035249 synaptic transmission, glutamatergic
GO:0035524 proline transmembrane transport
GO:0050890 cognition
GO:0055085 transmembrane transport
GO:1902476 chloride transmembrane transport
Cellular Component
GO:0005813 centrosome
GO:0005815 microtubule organizing center
GO:0005882 intermediate filament
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0030425 dendrite
GO:0042470 melanosome
GO:0043025 neuronal cell body
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000020142
View Gene Order
ENSBTAG00000007763
Not yet available
Pathways
NETPATH
REACTOME
REACT_13796
Amino acid transport across the plasma membrane pathway
REACT_19397
Transport of inorganic cations/anions and amino acids/oligopeptides pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_19118
SLC-mediated transmembrane transport pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.654352
RefSeq NM_001193493 NM_003038 XM_006712079
HUGO
OMIM
CCDS CCDS1879 CCDS54362
HPRD 02576
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca