Homo sapiens Gene: IFNE
Summary
InnateDB Gene IDBG-54354.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol IFNE
Gene Name interferon, epsilon
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000184995
Encoded Proteins
interferon, epsilon
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation from Orthologs
Summary
[Mus musculus] IFNE is constitutively expressed by epithelial cells of the female reproductive tract to confer protection against sexually transmitted infections.
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 9:21480839-21482313
Strand Reverse strand
Band p21.3
Transcripts
ENST00000448696 ENSP00000418018
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005125 cytokine activity
GO:0005126 cytokine receptor binding
GO:0005132 type I interferon receptor binding
Biological Process
GO:0002250 adaptive immune response
GO:0002286 T cell activation involved in immune response
GO:0002323 natural killer cell activation involved in immune response
GO:0006952 defense response
GO:0006959 humoral immune response
GO:0019221 cytokine-mediated signaling pathway
GO:0030183 B cell differentiation
GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein
GO:0042100 B cell proliferation
GO:0042742 defense response to bacterium
GO:0043330 response to exogenous dsRNA
GO:0045087 innate immune response
GO:0045343 regulation of MHC class I biosynthetic process
GO:0051607 defense response to virus
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
KEGG
Cytokine-cytokine receptor interaction pathway
RIG-I-like receptor signaling pathway pathway
Jak-STAT signaling pathway pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt Q86WN2
TrEMBL
UniProt Splice Variant
Entrez Gene 338376
UniGene Hs.682604
RefSeq NM_176891
HUGO HGNC:18163
OMIM 615223
CCDS CCDS34997
HPRD
IMGT
EMBL AY190045 AY358570 BC100871 BC100872 BC100873
GenPept AAI00872 AAI00873 AAI00874 AAO38686 AAQ88933
RNA Seq Atlas 338376