Homo sapiens Gene: PLXND1
Summary
InnateDB Gene IDBG-56134.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PLXND1
Gene Name plexin D1
Synonyms PLEXD1;
Species Homo sapiens
Ensembl Gene ENSG00000004399
Encoded Proteins
plexin D1
plexin D1
plexin D1
plexin D1
plexin D1
plexin D1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 3:129555175-129606818
Strand Reverse strand
Band q22.1
Transcripts
ENST00000324093 ENSP00000317128
ENST00000501038
ENST00000504689 ENSP00000426162
ENST00000504524
ENST00000512744 ENSP00000426540
ENST00000506979 ENSP00000427696
ENST00000508630
ENST00000512807
ENST00000504979
ENST00000503166
ENST00000514990
ENST00000504767
ENST00000511018
ENST00000515191
ENST00000505505
ENST00000505665 ENSP00000423832
ENST00000505237 ENSP00000426241
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004872 receptor activity
GO:0005515 protein binding
GO:0017154 semaphorin receptor activity
GO:0019904 protein domain specific binding
Biological Process
GO:0001525 angiogenesis
GO:0001569 patterning of blood vessels
GO:0003151 outflow tract morphogenesis
GO:0007165 signal transduction
GO:0007275 multicellular organismal development
GO:0007411 axon guidance
GO:0007416 synapse assembly
GO:0030334 regulation of cell migration
GO:0032092 positive regulation of protein binding
GO:0043542 endothelial cell migration
GO:0045765 regulation of angiogenesis
GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching
GO:0071526 semaphorin-plexin signaling pathway
Cellular Component
GO:0005622 intracellular
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
GO:0030027 lamellipodium
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
Developmental Biology pathway
Semaphorin interactions pathway
Other semaphorin interactions pathway
Axon guidance pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Plexin-D1 Signaling
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.301685
RefSeq NM_015103
HUGO
OMIM
CCDS CCDS33854
HPRD 05046
IMGT
EMBL
GenPept
RNA Seq Atlas