Version 5.4
Homo sapiens Gene: PLXND1
Summary
InnateDB Gene IDBG-56134.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PLXND1
Gene Name plexin D1
Synonyms PLEXD1
Species Homo sapiens
Ensembl Gene ENSG00000004399
Encoded Proteins
IDBP-56136
plexin D1
IDBP-476981
plexin D1
IDBP-478771
plexin D1
IDBP-474333
plexin D1
IDBP-476980
plexin D1
IDBP-476658
plexin D1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 3:129555175-129606818
Strand Reverse strand
Band q22.1
Transcripts
ENST00000324093 ENSP00000317128
ENST00000501038
ENST00000504689 ENSP00000426162
ENST00000504524
ENST00000512744 ENSP00000426540
ENST00000506979 ENSP00000427696
ENST00000508630
ENST00000512807
ENST00000504979
ENST00000503166
ENST00000514990
ENST00000504767
ENST00000511018
ENST00000515191
ENST00000505505
ENST00000505665 ENSP00000423832
ENST00000505237 ENSP00000426241
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004872 receptor activity
GO:0005515 protein binding
GO:0017154 semaphorin receptor activity
GO:0019904 protein domain specific binding
Biological Process
GO:0001525 angiogenesis
GO:0001569 patterning of blood vessels
GO:0003151 outflow tract morphogenesis
GO:0007165 signal transduction
GO:0007275 multicellular organismal development
GO:0007411 axon guidance
GO:0007416 synapse assembly
GO:0030334 regulation of cell migration
GO:0032092 positive regulation of protein binding
GO:0043542 endothelial cell migration
GO:0045765 regulation of angiogenesis
GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching
GO:0071526 semaphorin-plexin signaling pathway
Cellular Component
GO:0005622 intracellular
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
GO:0030027 lamellipodium
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000030123
View Gene Order
ENSBTAG00000001814
Not yet available
Pathways
NETPATH
REACTOME
REACT_19200
Other semaphorin interactions pathway
REACT_111045
Developmental Biology pathway
REACT_19271
Semaphorin interactions pathway
REACT_18266
Axon guidance pathway
KEGG
INOH
PID NCI
plexind1_pathway
Plexin-D1 Signaling
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.301685
RefSeq NM_015103
HUGO
OMIM
CCDS CCDS33854
HPRD 05046
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca