Version 5.4
Homo sapiens Gene: MYLK4
Summary
InnateDB Gene IDBG-56410.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MYLK4
Gene Name myosin light chain kinase family, member 4
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000145949
Encoded Proteins
IDBP-56412
myosin light chain kinase family, member 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 6:2663629-2750966
Strand Reverse strand
Band p25.2
Transcripts
ENST00000274643 ENSP00000274643
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
GO:0016773 phosphotransferase activity, alcohol group as acceptor
Biological Process
GO:0006468 protein phosphorylation
GO:0009103 lipopolysaccharide biosynthetic process
Cellular Component
GO:0016020 membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000044951
View Gene Order
ENSBTAG00000012079
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa04810
Regulation of actin cytoskeleton pathway
hsa04510
Focal adhesion pathway
hsa04020
Calcium signaling pathway pathway
hsa04270
Vascular smooth muscle contraction pathway
hsa04971
Gastric acid secretion pathway
INOH
PID NCI
Cross-References
SwissProt Q86YV6
TrEMBL
UniProt Splice Variant
Entrez Gene 340156
UniGene Hs.127830
RefSeq NM_001012418 XM_005249077 XM_005249078 XM_005249079 XM_006715081 XM_006715082 XM_006715083 XM_006715084
HUGO HGNC:27972
OMIM
CCDS CCDS34330
HPRD
IMGT
EMBL AK122581 AL138876 AL139092 BC132831 BC132833
GenPept AAI32832 AAI32834 BAC56922 CAI12221
RNA Seq Atlas 340156

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca