Version 5.4
Homo sapiens Gene: VPS51
Summary
InnateDB Gene IDBG-56462.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol VPS51
Gene Name vacuolar protein sorting 51 homolog (S. cerevisiae)
Synonyms ANG2; ANG3; C11orf2; C11orf3; FFR
Species Homo sapiens
Ensembl Gene ENSG00000149823
Encoded Proteins
IDBP-56464
chromosome 11 open reading frame 2
IDBP-585703
chromosome 11 open reading frame 2
IDBP-595275
chromosome 11 open reading frame 2
IDBP-598681
chromosome 11 open reading frame 2
IDBP-584768
chromosome 11 open reading frame 2
IDBP-587665
chromosome 11 open reading frame 2
IDBP-591557
chromosome 11 open reading frame 2
IDBP-600541
chromosome 11 open reading frame 2
IDBP-600520
chromosome 11 open reading frame 2
IDBP-602566
chromosome 11 open reading frame 2
IDBP-590437
chromosome 11 open reading frame 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the vacuolar protein sorting-associated protein 51 family. The encoded protein is a component of the Golgi-associated retrograde protein complex which acts as a tethering factor for carriers in retrograde transport from the early and late endosomes to the trans-Golgi network. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:65089324-65111860
Strand Forward strand
Band q13.1
Transcripts
ENST00000279281 ENSP00000279281
ENST00000528588 ENSP00000436134
ENST00000530773 ENSP00000434138
ENST00000528050
ENST00000533656
ENST00000534124 ENSP00000436867
ENST00000529180 ENSP00000435245
ENST00000533487 ENSP00000433579
ENST00000526578 ENSP00000431188
ENST00000534557 ENSP00000435691
ENST00000527646
ENST00000531146
ENST00000533827 ENSP00000434542
ENST00000534591
ENST00000526856 ENSP00000435629
ENST00000530673 ENSP00000431317
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 25 experimentally validated interaction(s) in this database.
Experimentally validated
Total 25 [view]
Protein-Protein 24 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0006869 lipid transport
GO:0006893 Golgi to plasma membrane transport
GO:0006914 autophagy
GO:0007067 mitotic nuclear division
GO:0015031 protein transport
GO:0042147 retrograde transport, endosome to Golgi
Cellular Component
GO:0000145 exocyst
GO:0000775 chromosome, centromeric region
GO:0000938 GARP complex
GO:0005634 nucleus
GO:0005794 Golgi apparatus
GO:0016021 integral component of membrane
GO:0017119 Golgi transport complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000024797
View Gene Order
ENSBTAG00000015499
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 738
UniGene Hs.277517
RefSeq NM_013265
HUGO HGNC:1172
OMIM 615738
CCDS CCDS8093
HPRD 12605
IMGT
EMBL
GenPept
RNA Seq Atlas 738

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca