Version 5.4
Homo sapiens Gene: OVOL2
Summary
InnateDB Gene IDBG-56804.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol OVOL2
Gene Name ovo-like 2 (Drosophila)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000125850
Encoded Proteins
IDBP-56806
ovo-like 2 (Drosophila)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 20:17956979-18059188
Strand Reverse strand
Band p11.23
Transcripts
ENST00000278780 ENSP00000278780
ENST00000486776
ENST00000483661
ENST00000494030
ENST00000462208
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0003677 DNA binding
GO:0044212 transcription regulatory region DNA binding
GO:0046872 metal ion binding
Biological Process
GO:0001525 angiogenesis
GO:0001755 neural crest cell migration
GO:0001842 neural fold formation
GO:0001947 heart looping
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0006366 transcription from RNA polymerase II promoter
GO:0007507 heart development
GO:0008285 negative regulation of cell proliferation
GO:0009953 dorsal/ventral pattern formation
GO:0010719 negative regulation of epithelial to mesenchymal transition
GO:0010837 regulation of keratinocyte proliferation
GO:0010944 negative regulation of transcription by competitive promoter binding
GO:0045617 negative regulation of keratinocyte differentiation
GO:0045746 negative regulation of Notch signaling pathway
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0048557 embryonic digestive tract morphogenesis
GO:0051726 regulation of cell cycle
GO:0060214 endocardium formation
GO:0060347 heart trabecula formation
GO:0060716 labyrinthine layer blood vessel development
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000037279
View Gene Order
ENSBTAG00000008410
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.661013 Hs.710157
RefSeq NM_021220
HUGO
OMIM
CCDS CCDS13132
HPRD 15780
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca