Version 5.4
Homo sapiens Gene: BPHL
Summary
InnateDB Gene IDBG-57412.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BPHL
Gene Name biphenyl hydrolase-like (serine hydrolase)
Synonyms BPH-RP; MCNAA; VACVASE
Species Homo sapiens
Ensembl Gene ENSG00000137274
Encoded Proteins
IDBP-57414
biphenyl hydrolase-like (serine hydrolase)
IDBP-57416
biphenyl hydrolase-like (serine hydrolase)
IDBP-57418
biphenyl hydrolase-like (serine hydrolase)
IDBP-360782
biphenyl hydrolase-like (serine hydrolase)
IDBP-360789
biphenyl hydrolase-like (serine hydrolase)
IDBP-360805
biphenyl hydrolase-like (serine hydrolase)
IDBP-360846
biphenyl hydrolase-like (serine hydrolase)
IDBP-360847
biphenyl hydrolase-like (serine hydrolase)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the serine protease family of hydrolytic enzymes which contain a serine in their active site. The encoded protein may play a role in activation of the antiviral prodrug valacyclovir. Alternatively spliced transcript variants have been described.[provided by RefSeq, Jan 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:3118374-3153578
Strand Forward strand
Band p25.2
Transcripts
ENST00000380379 ENSP00000369739
ENST00000380375 ENSP00000369734
ENST00000380368 ENSP00000369726
ENST00000434640 ENSP00000390472
ENST00000430655 ENSP00000396637
ENST00000424847 ENSP00000394072
ENST00000433912 ENSP00000413762
ENST00000423798 ENSP00000395744
ENST00000490918
ENST00000479273
ENST00000488487
ENST00000464040
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 3 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0016787 hydrolase activity
Biological Process
GO:0006520 cellular amino acid metabolic process
GO:0008152 metabolic process
GO:0009636 response to toxic substance
Cellular Component
GO:0005739 mitochondrion
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Gene ID
Gene Order
ENSMUSG00000038286
View Gene Order
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.733339
RefSeq NM_004332
HUGO
OMIM
CCDS CCDS4483
HPRD 04403
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca