Homo sapiens Gene: AQP7
Summary
InnateDB Gene IDBG-57837.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol AQP7
Gene Name aquaporin 7
Synonyms AQP7L; AQP9; AQPap; GLYCQTL;
Species Homo sapiens
Ensembl Gene ENSG00000165269
Encoded Proteins
aquaporin 7
aquaporin 7
aquaporin 7
aquaporin 7
aquaporin 7
aquaporin 7
aquaporin 7
aquaporin 7
aquaporin 7
aquaporin 7
aquaporin 7
aquaporin 7
aquaporin 7
aquaporin 7
aquaporin 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Aquaporins/major intrinsic protein (MIP) are a family of water-selective membrane channels. Aquaporin 7 has greater sequence similarity with AQP3 and AQP9 and they may be a subfamily. Aquaporin 7 and AQP3 are at the same chromosomal location suggesting that 9p13 may be a site of an aquaporin cluster. Aquaporin 7 facilitates water, glycerol and urea transport. It may play an important role in sperm function. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:33383179-33402682
Strand Reverse strand
Band p13.3
Transcripts
ENST00000297988 ENSP00000297988
ENST00000379507 ENSP00000368821
ENST00000379506 ENSP00000368820
ENST00000379503
ENST00000377425 ENSP00000396111
ENST00000447660 ENSP00000412868
ENST00000439678 ENSP00000410138
ENST00000539936 ENSP00000439534
ENST00000537089 ENSP00000441619
ENST00000623097
ENST00000624075 ENSP00000485332
ENST00000624890 ENSP00000485131
ENST00000624005 ENSP00000485224
ENST00000624420 ENSP00000485348
ENST00000624095 ENSP00000485419
ENST00000625109 ENSP00000485081
ENST00000624432
ENST00000623743
ENST00000625032 ENSP00000485246
ENST00000623519
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005215 transporter activity
GO:0015250 water channel activity
GO:0015254 glycerol channel activity
Biological Process
GO:0006091 generation of precursor metabolites and energy
GO:0006810 transport
GO:0006833 water transport
GO:0007588 excretion
GO:0015793 glycerol transport
GO:0055085 transmembrane transport
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005911 cell-cell junction
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
Transmembrane transport of small molecules pathway
Passive transport by Aquaporins pathway
Transport of glycerol from adipocytes to the liver by Aquaporins pathway
Aquaporin-mediated transport pathway
KEGG
PPAR signaling pathway pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 364
UniGene
RefSeq NM_001170 XM_003403755 XM_005251453
HUGO HGNC:640
OMIM 602974
CCDS CCDS6541
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas 100509620 101930168 102724507 364