Homo sapiens Gene: COPB2
Summary
InnateDB Gene IDBG-58841.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol COPB2
Gene Name coatomer protein complex, subunit beta 2 (beta prime)
Synonyms beta\'-COP;
Species Homo sapiens
Ensembl Gene ENSG00000184432
Encoded Proteins
coatomer protein complex, subunit beta 2 (beta prime)
coatomer protein complex, subunit beta 2 (beta prime)
coatomer protein complex, subunit beta 2 (beta prime)
coatomer protein complex, subunit beta 2 (beta prime)
coatomer protein complex, subunit beta 2 (beta prime)
coatomer protein complex, subunit beta 2 (beta prime)
coatomer protein complex, subunit beta 2 (beta prime)
coatomer protein complex, subunit beta 2 (beta prime)
coatomer protein complex, subunit beta 2 (beta prime)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The Golgi coatomer complex (see MIM 601924) constitutes the coat of nonclathrin-coated vesicles and is essential for Golgi budding and vesicular trafficking. It consists of 7 protein subunits, including COPB2.[supplied by OMIM, Jul 2002]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:139355600-139389732
Strand Reverse strand
Band q23
Transcripts
ENST00000333188 ENSP00000329419
ENST00000503326 ENSP00000426682
ENST00000507777 ENSP00000422295
ENST00000502734
ENST00000512309 ENSP00000422917
ENST00000510181
ENST00000515006 ENSP00000423271
ENST00000512153 ENSP00000422547
ENST00000513274 ENSP00000424144
ENST00000512242 ENSP00000427185
ENST00000510491
ENST00000514508 ENSP00000422469
ENST00000504295
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 53 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 53 [view]
Protein-Protein 51 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005198 structural molecule activity
GO:0005515 protein binding
Biological Process
GO:0006886 intracellular protein transport
GO:0006890 retrograde vesicle-mediated transport, Golgi to ER
GO:0006891 intra-Golgi vesicle-mediated transport
GO:0016192 vesicle-mediated transport
GO:0048205 COPI coating of Golgi vesicle
GO:0061024 membrane organization
Cellular Component
GO:0005829 cytosol
GO:0030117 membrane coat
GO:0030126 COPI vesicle coat
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Not yet available
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Pathways
NETPATH
TNFalpha pathway
REACTOME
COPI Mediated Transport pathway
Golgi to ER Retrograde Transport pathway
Membrane Trafficking pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt P35606
TrEMBL B4DZI8 D6R997 D6RBG7 D6RBT6 D6RBZ7 D6RCL6 H0Y938
UniProt Splice Variant
Entrez Gene 9276
UniGene Hs.600506 Hs.681616
RefSeq NM_004766
HUGO HGNC:2232
OMIM 606990
CCDS CCDS3108
HPRD
IMGT
EMBL AC024933 AK302943 BC000326 CH471052 X70476
GenPept AAH00326 BAG64100 CAA49900 EAW79040
RNA Seq Atlas 9276