Mus musculus Gene: Gcom1
Summary
InnateDB Gene IDBG-605920.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gcom1
Gene Name GRINL1A complex locus
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000092137
Encoded Proteins
glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A
glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A
glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A
glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000137878:
This gene encodes a protein that is abundantly expressed in cardiac tissue. The encoded protein localizes to intercalated discs in cardiomyocytes and functions as an activator of Rho-dependent serum-response factor signaling. Alternate splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstreamstream gene POLR2M (polymerase (RNA) II (DNA directed) polypeptide M). [provided by RefSeq, Nov 2011] This locus represents naturally occurring readthrough transcription between the neighboring MYZAP (myocardial zonula adherens protein) and POLR2M (polymerase (RNA) II (DNA directed) polypeptide M) genes on chromosome 15. Alternate splicing results in two readthrough transcript variants that encode different isoforms. One of the readthrough variants encodes a fusion protein that shares sequence identity with each individual gene product. The other variant encodes a protein that shares sequence identity with the upstream gene product but its C-terminal region is distinct due to frameshifts relative to the downstream gene. [provided by RefSeq, Nov 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:71479325-71592265
Strand Reverse strand
Band D
Transcripts
ENSMUST00000166843 ENSMUSP00000128698
ENSMUST00000164962 ENSMUSP00000131353
ENSMUST00000165936 ENSMUSP00000127356
ENSMUST00000163998 ENSMUSP00000131267
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.
Predicted by orthology
Total 17 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0008150 biological_process
GO:0035556 intracellular signal transduction
Cellular Component
GO:0005575 cellular_component
GO:0016591 DNA-directed RNA polymerase II, holoenzyme
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq
OMIM
CCDS
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas