Version 5.4
Homo sapiens Gene: ASTL
Summary
InnateDB Gene IDBG-61482.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ASTL
Gene Name astacin-like metallo-endopeptidase (M12 family)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000188886
Encoded Proteins
IDBP-61484
astacin-like metallo-endopeptidase (M12 family)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 2:96123850-96138436
Strand Reverse strand
Band q11.2
Transcripts
ENST00000342380 ENSP00000343674
ENST00000470582
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004222 metalloendopeptidase activity
GO:0005515 protein binding
GO:0008233 peptidase activity
GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding
GO:0070001 aspartic-type peptidase activity
GO:0070002 glutamic-type peptidase activity
Biological Process
GO:0006508 proteolysis
GO:0007155 cell adhesion
GO:0009566 fertilization
GO:0010954 positive regulation of protein processing
GO:0060468 prevention of polyspermy
GO:2000360 negative regulation of binding of sperm to zona pellucida
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0030133 transport vesicle
GO:0060473 cortical granule
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000050468
View Gene Order
ENSBTAG00000020348
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.447993
RefSeq NM_001002036
HUGO
OMIM
CCDS CCDS33249
HPRD 16396
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca