Version 5.4
Homo sapiens Gene: AADAC
Summary
InnateDB Gene IDBG-61653.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol AADAC
Gene Name arylacetamide deacetylase
Synonyms CES5A1; DAC
Species Homo sapiens
Ensembl Gene ENSG00000114771
Encoded Proteins
IDBP-61655
arylacetamide deacetylase (esterase)
IDBP-478631
arylacetamide deacetylase (esterase)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Microsomal arylacetamide deacetylase competes against the activity of cytosolic arylamine N-acetyltransferase, which catalyzes one of the initial biotransformation pathways for arylamine and heterocyclic amine carcinogens [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:151814037-151828488
Strand Forward strand
Band q25.1
Transcripts
ENST00000232892 ENSP00000232892
ENST00000488869 ENSP00000419620
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004806 triglyceride lipase activity
GO:0016298 lipase activity
GO:0016787 hydrolase activity
GO:0017171 serine hydrolase activity
GO:0019213 deacetylase activity
GO:0052689 carboxylic ester hydrolase activity
Biological Process
GO:0008152 metabolic process
GO:0010898 positive regulation of triglyceride catabolic process
Cellular Component
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000027761
View Gene Order
ENSBTAG00000011569
Not yet available
Cross-References
SwissProt
TrEMBL C9K0E9
UniProt Splice Variant
Entrez Gene 13
UniGene Hs.506908
RefSeq NM_001086 XM_005247103
HUGO HGNC:17
OMIM 600338
CCDS CCDS33877
HPRD 02640
IMGT
EMBL AC068647
GenPept
RNA Seq Atlas 13

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca