Homo sapiens Gene: LAMA1
Summary
InnateDB Gene IDBG-617.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LAMA1
Gene Name laminin, alpha 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000101680
Encoded Proteins
laminin, alpha 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 18:6941744-7117814
Strand Reverse strand
Band p11.31
Transcripts
ENST00000389658 ENSP00000374309
ENST00000488064
ENST00000492048
ENST00000488089
ENST00000490190
ENST00000484335
ENST00000585178
ENST00000579014
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated
Total 11 [view]
Protein-Protein 11 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005102 receptor binding
GO:0005201 extracellular matrix structural constituent
GO:0005515 protein binding
GO:0043208 glycosphingolipid binding
Biological Process
GO:0002011 morphogenesis of an epithelial sheet
GO:0007155 cell adhesion
GO:0007166 cell surface receptor signaling pathway
GO:0007411 axon guidance
GO:0009888 tissue development
GO:0030155 regulation of cell adhesion
GO:0030198 extracellular matrix organization
GO:0030334 regulation of cell migration
GO:0031175 neuron projection development
GO:0045198 establishment of epithelial cell apical/basal polarity
GO:0045995 regulation of embryonic development
GO:0060041 retina development in camera-type eye
GO:0060441 epithelial tube branching involved in lung morphogenesis
GO:0060445 branching involved in salivary gland morphogenesis
GO:0061304 retinal blood vessel morphogenesis
Cellular Component
GO:0005576 extracellular region
GO:0005578 proteinaceous extracellular matrix
GO:0005604 basement membrane
GO:0005606 laminin-1 complex
GO:0005608 laminin-3 complex
GO:0005615 extracellular space
GO:0005911 cell-cell junction
GO:0031012 extracellular matrix
GO:0043256 laminin complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
Alpha6Beta4Integrin pathway
REACTOME
Developmental Biology pathway
Extracellular matrix organization pathway
Axon guidance pathway
ECM proteoglycans pathway
Non-integrin membrane-ECM interactions pathway
L1CAM interactions pathway
Laminin interactions pathway
KEGG
Focal adhesion pathway
ECM-receptor interaction pathway
Toxoplasmosis pathway
Amoebiasis pathway
Pathways in cancer pathway
Small cell lung cancer pathway
INOH
PID BIOCARTA
Agrin in postsynaptic differentiation [Biocarta view]
PID NCI
Syndecan-2-mediated signaling events
Beta1 integrin cell surface interactions
Glypican 1 network
Alpha6 beta4 integrin-ligand interactions
Syndecan-4-mediated signaling events
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.270364
RefSeq NM_005559
HUGO
OMIM
CCDS CCDS32787
HPRD 01033
IMGT
EMBL
GenPept
RNA Seq Atlas