Bos taurus Gene: SORBS2 | |||||||
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Summary | |||||||
InnateDB Gene | IDBG-628561.3 | ||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
Gene Symbol | SORBS2 | ||||||
Gene Name | sorbin and SH3 domain-containing protein 2 | ||||||
Synonyms | Argbp2 | ||||||
Species | Bos taurus | ||||||
Ensembl Gene | ENSBTAG00000016486 | ||||||
Encoded Proteins |
sorbin and SH3 domain containing 2
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Protein Structure | |||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||
Entrez Gene | |||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000154556:
Arg and c-Abl represent the mammalian members of the Abelson family of non-receptor protein-tyrosine kinases. They interact with the Arg/Abl binding proteins via the SH3 domains present in the carboxy end of the latter group of proteins. This gene encodes the sorbin and SH3 domain containing 2 protein. It has three C-terminal SH3 domains and an N-terminal sorbin homology (SoHo) domain that interacts with lipid raft proteins. The subcellular localization of this protein in epithelial and cardiac muscle cells suggests that it functions as an adapter protein to assemble signaling complexes in stress fibers, and that it is a potential link between Abl family kinases and the actin cytoskeleton. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||
Type | Protein coding | ||||||
Genomic Location | Chromosome 27:14906506-15022818 | ||||||
Strand | Reverse strand | ||||||
Band | |||||||
Transcripts |
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Interactions | |||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 30 interaction(s) predicted by orthology.
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Orthologs | |||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Cross-References | |||||||
SwissProt | |||||||
TrEMBL | A0JN82 | ||||||
UniProt Splice Variant | |||||||
Entrez Gene | 614391 | ||||||
UniGene | Bt.107524 | ||||||
RefSeq | NM_001079787 | ||||||
HUGO | |||||||
OMIM | |||||||
CCDS | |||||||
HPRD | |||||||
IMGT | |||||||
EMBL | BC126558 DAAA02060197 DAAA02060198 | ||||||
GenPept | AAI26559 | ||||||
RNA Seq Atlas | 614391 | ||||||