Version 5.4
Bos taurus Gene: MARVELD2
Summary
InnateDB Gene IDBG-628658.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MARVELD2
Gene Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000040001
Encoded Proteins
IDBP-680027
MARVEL domain containing 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000152939:
The protein encoded by this gene is a membrane protein found at the tight junctions between epithelial cells. The encoded protein helps establish epithelial barriers such as those in the organ of Corti, where these barriers are required for normal hearing. Defects in this gene are a cause of deafness autosomal recessive type 49 (DFNB49). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 20:10244309-10265817
Strand Reverse strand
Band
Transcripts
ENSBTAT00000053818 ENSBTAP00000051825
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007605 sensory perception of sound
GO:0045216 cell-cell junction organization
GO:0061028 establishment of endothelial barrier
GO:0070830 tight junction assembly
Cellular Component
GO:0005737 cytoplasm
GO:0005923 tight junction
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016323 basolateral plasma membrane
GO:0016324 apical plasma membrane
GO:0031410 cytoplasmic vesicle
GO:0033010 paranodal junction
GO:0043220 Schmidt-Lanterman incisure
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000152939
View Gene Order
ENSMUSG00000021636
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_4
EGFR1 pathway
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F1MKJ9
UniProt Splice Variant
Entrez Gene 541110
UniGene Bt.11047
RefSeq XM_002696281 XM_005196131 XM_005221445 XM_614589
HUGO HGNC:26401
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02050051
GenPept
RNA Seq Atlas 541110
Transcript Frequencies
Tag Count based mRNA-Abundances across 87 different Tissues (TPM).

Based on Data from Bovine Gene Atlas

Tag Count based mRNA-Abundances across 87 different Tissues (TPM)

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If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca