InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: RBBP5

Summary

InnateDB Gene

IDBG-628742.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RBBP5

Gene Name

retinoblastoma-binding protein 5

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000015946

Encoded Proteins

IDBP-680120

retinoblastoma-binding protein 5

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000117222:
This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. The encoded protein binds directly to retinoblastoma protein, which regulates cell proliferation. It interacts preferentially with the underphosphorylated retinoblastoma protein via the E1A-binding pocket B. Three alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2010]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 16:2694854-2733979

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000021204

ENSBTAP00000021204

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 80 interaction(s) predicted by orthology.

Predicted by orthology
Total	80 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0035064	methylated histone binding
GO:0042800	histone methyltransferase activity (H3-K4 specific)
GO:0044212	transcription regulatory region DNA binding