InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: TNKS

Summary

InnateDB Gene

IDBG-628743.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TNKS

Gene Name

tankyrase-1

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000001463

Encoded Proteins

IDBP-680223

tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000173273:

Gene Information

Type

Protein coding

Genomic Location

Chromosome 27:24632930-24789416

Strand

Forward strand

Band

Transcripts

ENSBTAT00000001917

ENSBTAP00000001917

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 21 interaction(s) predicted by orthology.

Predicted by orthology
Total	21 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003950	NAD+ ADP-ribosyltransferase activity
GO:0005515	protein binding
GO:0008270	zinc ion binding

Biological Process

GO:0000209	protein polyubiquitination
GO:0006471	protein ADP-ribosylation
GO:0016055	Wnt signaling pathway
GO:0018105	peptidyl-serine phosphorylation
GO:0018107	peptidyl-threonine phosphorylation
GO:0032212	positive regulation of telomere maintenance via telomerase
GO:0043392	negative regulation of DNA binding
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0051225	spindle assembly
GO:0070198	protein localization to chromosome, telomeric region
GO:0070212	protein poly-ADP-ribosylation
GO:0070213	protein auto-ADP-ribosylation
GO:0090263	positive regulation of canonical Wnt signaling pathway

Cellular Component

GO:0000781	chromosome, telomeric region
GO:0000784	nuclear chromosome, telomeric region
GO:0005634	nucleus
GO:0005794	Golgi apparatus
GO:0005829	cytosol
GO:0031965	nuclear membrane