Bos taurus Gene: BT.62229 | |||||||
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Summary | |||||||
InnateDB Gene | IDBG-628746.3 | ||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
Gene Symbol | BT.62229 | ||||||
Gene Name | protein VAC14 homolog | ||||||
Synonyms | |||||||
Species | Bos taurus | ||||||
Ensembl Gene | ENSBTAG00000023795 | ||||||
Encoded Proteins |
protein VAC14 homolog
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Protein Structure | |||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||
Entrez Gene | |||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000103043:
The content of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) in endosomal membranes changes dynamically with fission and fusion events that generate or absorb intracellular transport vesicles. VAC14 is a component of a trimolecular complex that tightly regulates the level of PtdIns(3,5)P2. Other components of this complex are the PtdIns(3,5)P2-synthesizing enzyme PIKFYVE (MIM 609414) and the PtdIns(3,5)P2 phosphatase FIG4 (MIM 609390). VAC14 functions as an activator of PIKFYVE (Sbrissa et al., 2007 [PubMed 17556371]).[supplied by OMIM, Feb 2010] |
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Gene Information | |||||||
Type | Protein coding | ||||||
Genomic Location | Chromosome 18:1449428-1525767 | ||||||
Strand | Forward strand | ||||||
Band | |||||||
Transcripts |
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Interactions | |||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
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Gene Ontology | |||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Pathway Predictions based on Human Orthology Data | |||||||
NETPATH | |||||||
REACTOME |
Synthesis of PIPs at the early endosome membrane pathway
Synthesis of PIPs at the Golgi membrane pathway
Synthesis of PIPs at the late endosome membrane pathway
Synthesis of PIPs at the early endosome membrane pathway
Synthesis of PIPs at the late endosome membrane pathway
Synthesis of PIPs at the Golgi membrane pathway
Metabolism of lipids and lipoproteins pathway
PI Metabolism pathway
Metabolism pathway
Metabolism of lipids and lipoproteins pathway
PI Metabolism pathway
Phospholipid metabolism pathway
Phospholipid metabolism pathway
Metabolism pathway
Synthesis of PIPs at the early endosome membrane pathway
Synthesis of PIPs at the late endosome membrane pathway
Synthesis of PIPs at the Golgi membrane pathway
PI Metabolism pathway
Metabolism pathway
Metabolism of lipids and lipoproteins pathway
Phospholipid metabolism pathway
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KEGG | |||||||
INOH | |||||||
PID NCI | |||||||
Cross-References | |||||||
SwissProt | |||||||
TrEMBL | F1MJZ1 | ||||||
UniProt Splice Variant | |||||||
Entrez Gene | 533202 | ||||||
UniGene | Bt.62229 | ||||||
RefSeq | NM_001082444 | ||||||
HUGO | |||||||
OMIM | |||||||
CCDS | |||||||
HPRD | |||||||
IMGT | |||||||
EMBL | DAAA02045964 DAAA02045965 | ||||||
GenPept | |||||||
RNA Seq Atlas | 533202 | ||||||