Version 5.4
Bos taurus Gene: BT.105276
Summary
InnateDB Gene IDBG-629177.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.105276
Gene Name polymeric immunoglobulin receptor precursor
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000019798
Encoded Proteins
IDBP-680580
polymeric immunoglobulin receptor precursor
IDBP-680581
polymeric immunoglobulin receptor precursor
IDBP-680587
polymeric immunoglobulin receptor precursor
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000162896:
This gene is a member of the immunoglobulin superfamily. The encoded poly-Ig receptor binds polymeric immunoglobulin molecules at the basolateral surface of epithelial cells; the complex is then transported across the cell to be secreted at the apical surface. A significant association was found between immunoglobulin A nephropathy and several SNPs in this gene.[provided by RefSeq, Sep 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:4533505-4551569
Strand Reverse strand
Band
Transcripts
ENSBTAT00000026377 ENSBTAP00000026377
ENSBTAT00000063804 ENSBTAP00000056364
ENSBTAT00000054718 ENSBTAP00000050920
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001792 polymeric immunoglobulin receptor activity
GO:0005515 protein binding
Biological Process
GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste
GO:0001895 retina homeostasis
GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor
GO:0007173 epidermal growth factor receptor signaling pathway
GO:0038093 Fc receptor signaling pathway
GO:0043113 receptor clustering
Cellular Component
GO:0005615 extracellular space
GO:0005886 plasma membrane
GO:0043235 receptor complex
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000162896
View Gene Order
ENSMUSG00000026417
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa04672
Intestinal immune network for IgA production pathway
mmu04672
Intestinal immune network for IgA production pathway
INOH
PID NCI
il4_2pathway
IL4-mediated signaling events
Cross-References
SwissProt
TrEMBL F6PQI6 G5E6M1
UniProt Splice Variant
Entrez Gene 281401
UniGene Bt.4695
RefSeq NM_174143
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02041974 DAAA02041975
GenPept
RNA Seq Atlas 281401

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca