Version 5.4
Bos taurus Gene: TRIM13
Summary
InnateDB Gene IDBG-629232.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TRIM13
Gene Name E3 ubiquitin-protein ligase TRIM13
Synonyms RFP2
Species Bos taurus
Ensembl Gene ENSBTAG00000008173
Encoded Proteins
IDBP-680626
tripartite motif-containing protein 13
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation from Orthologs
Summary
PMID 23438823
[Homo sapiens] TRIM13 was identified in a systematic screen for positive regulators of innate immune responses.
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000204977:
This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This gene is located on chromosome 13 within the minimal deletion region for B-cell chronic lymphocytic leukemia. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:19543053-19556013
Strand Forward strand
Band
Transcripts
ENSBTAT00000010745 ENSBTAP00000010745
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004842 ubiquitin-protein transferase activity
GO:0004871 signal transducer activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0016874 ligase activity
GO:0046872 metal ion binding
Biological Process
GO:0007165 signal transduction
GO:0010332 response to gamma radiation
GO:0010942 positive regulation of cell death
GO:0016239 positive regulation of macroautophagy
GO:0016567 protein ubiquitination
GO:0030433 ER-associated ubiquitin-dependent protein catabolic process
GO:0032897 negative regulation of viral transcription
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0045087 innate immune response
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:0051865 protein autoubiquitination
GO:1902187 negative regulation of viral release from host cell
Cellular Component
GO:0005622 intracellular
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0097038 perinuclear endoplasmic reticulum
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000204977
View Gene Order
ENSMUSG00000035235
View Gene Order
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.5644
RefSeq NM_001038165 XM_005213657
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca