InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: SAP30

Summary

InnateDB Gene

IDBG-629305.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SAP30

Gene Name

histone deacetylase complex subunit SAP30

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000015578

Encoded Proteins

IDBP-680707

Sin3A-associated protein, 30kDa

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000164105:
Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP18, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This complex is active in deacetylating core histone octamers, but inactive in deacetylating nucleosomal histones. A pseudogene of this gene is located on chromosome 3. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 8:5610648-5615594

Strand

Forward strand

Band

Transcripts

ENSBTAT00000020692

ENSBTAP00000020692

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 32 interaction(s) predicted by orthology.

Predicted by orthology
Total	32 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003714	transcription corepressor activity
GO:0005515	protein binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0006355	regulation of transcription, DNA-templated
GO:0035914	skeletal muscle cell differentiation