Version 5.4
Bos taurus Gene: ABCE1
Summary
InnateDB Gene IDBG-629486.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ABCE1
Gene Name ATP-binding cassette sub-family E member 1
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000019854
Encoded Proteins
IDBP-680891
ATP-binding cassette sub-family E member 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000164163:
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. Alternatively referred to as the RNase L inhibitor, this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system, the central pathway for viral interferon action. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:13333870-13364710
Strand Reverse strand
Band
Transcripts
ENSBTAT00000048747 ENSBTAP00000045734
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0005524 ATP binding
GO:0016887 ATPase activity
GO:0017111 nucleoside-triphosphatase activity
GO:0051536 iron-sulfur cluster binding
Biological Process
GO:0006200 ATP catabolic process
GO:0008152 metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000164163
View Gene Order
ENSMUSG00000058355
View Gene Order
Cross-References
SwissProt
TrEMBL A4IFE6
UniProt Splice Variant
Entrez Gene 514991
UniGene Bt.30768
RefSeq NM_001083685 XM_005217499
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC134545 DAAA02044342
GenPept AAI34546
RNA Seq Atlas 514991

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca