Version 5.4
| Bos taurus Gene: HMGCS1 | |||||||
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| Summary | |||||||
| InnateDB Gene | IDBG-629579.3 | ||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
| Gene Symbol | HMGCS1 | ||||||
| Gene Name | hydroxymethylglutaryl-CoA synthase, cytoplasmic | ||||||
| Synonyms | |||||||
| Species | Bos taurus | ||||||
| Ensembl Gene | ENSBTAG00000011839 | ||||||
| Encoded Proteins |
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
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| Protein Structure | |||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||
| Entrez Gene | |||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000112972:
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| Gene Information | |||||||
| Type | Protein coding | ||||||
| Genomic Location | Chromosome 20:31451386-31474239 | ||||||
| Strand | Forward strand | ||||||
| Band | |||||||
| Transcripts |
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| Interactions | |||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Pathway Predictions based on Human Orthology Data | |||||||
| NETPATH | |||||||
| REACTOME |
PPARA activates gene expression pathway
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) pathway
Activation of gene expression by SREBF (SREBP) pathway
Regulation of cholesterol biosynthesis by SREBP (SREBF) pathway
Cholesterol biosynthesis pathway
Fatty acid, triacylglycerol, and ketone body metabolism pathway
Metabolism of lipids and lipoproteins pathway
Metabolism pathway
Fatty acid, triacylglycerol, and ketone body metabolism pathway
Activation of gene expression by SREBF (SREBP) pathway
Regulation of cholesterol biosynthesis by SREBP (SREBF) pathway
Metabolism pathway
Metabolism of lipids and lipoproteins pathway
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) pathway
Cholesterol biosynthesis pathway
PPARA activates gene expression pathway
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| KEGG |
Terpenoid backbone biosynthesis pathway
Valine, leucine and isoleucine degradation pathway
Butanoate metabolism pathway
Synthesis and degradation of ketone bodies pathway
Valine, leucine and isoleucine degradation pathway
Synthesis and degradation of ketone bodies pathway
Terpenoid backbone biosynthesis pathway
Butanoate metabolism pathway
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| INOH |
Butanoate metabolism pathway
Valine Leucine Isoleucine degradation pathway
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| PID NCI |
FOXA2 and FOXA3 transcription factor networks
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| Cross-References | |||||||
| SwissProt | |||||||
| TrEMBL | F6RJG0 | ||||||
| UniProt Splice Variant | |||||||
| Entrez Gene | 407767 | ||||||
| UniGene | Bt.49542 | ||||||
| RefSeq | NM_001206578 XM_005221541 XM_005221542 XM_005221543 XM_005221544 XM_005221545 | ||||||
| HUGO | HGNC:5007 | ||||||
| OMIM | |||||||
| CCDS | |||||||
| HPRD | |||||||
| IMGT | |||||||
| EMBL | DAAA02050503 | ||||||
| GenPept | |||||||
| RNA Seq Atlas | 407767 | ||||||