InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: BT.79602

Summary

InnateDB Gene

IDBG-629623.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BT.79602

Gene Name

frizzled-3 precursor

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000035084

Encoded Proteins

IDBP-681028

Uncharacterized protein

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000104290:
This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. The function of this protein is unknown, although it may play a role in mammalian hair follicle development. Alternative splicing results in multiple transcript variants. This gene is a susceptibility locus for schizophrenia. [provided by RefSeq, Dec 2010]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 8:10002972-10091175

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000061597

ENSBTAP00000053192

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004888	transmembrane signaling receptor activity
GO:0005515	protein binding
GO:0042813	Wnt-activated receptor activity

Biological Process

GO:0001736	establishment of planar polarity
GO:0001764	neuron migration
GO:0001843	neural tube closure
GO:0001942	hair follicle development
GO:0007166	cell surface receptor signaling pathway
GO:0007275	multicellular organismal development
GO:0016055	Wnt signaling pathway
GO:0030901	midbrain development
GO:0033278	cell proliferation in midbrain
GO:0036342	post-anal tail morphogenesis
GO:0042472	inner ear morphogenesis
GO:0071679	commissural neuron axon guidance

Cellular Component

GO:0005886	plasma membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0016324	apical plasma membrane
GO:0016328	lateral plasma membrane
GO:0030424	axon
GO:0030425	dendrite
GO:0043025	neuronal cell body
GO:0045177	apical part of cell
GO:0048786	presynaptic active zone