Version 5.4
Bos taurus Gene: SEPT6
Summary
InnateDB Gene IDBG-629695.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SEPT6
Gene Name Septin-6
Synonyms SEPT11
Species Bos taurus
Ensembl Gene ENSBTAG00000004291
Encoded Proteins
IDBP-681116
Septin-6
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000125354:
This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis. One version of pediatric acute myeloid leukemia is the result of a reciprocal translocation between chromosomes 11 and X, with the breakpoint associated with the genes encoding the mixed-lineage leukemia and septin 2 proteins. This gene encodes four transcript variants encoding three distinct isoforms. An additional transcript variant has been identified, but its biological validity has not been determined. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome X:3819817-3889945
Strand Reverse strand
Band
Transcripts
ENSBTAT00000005629 ENSBTAP00000005629
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.
Predicted by orthology
Total 16 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0005515 protein binding
GO:0005525 GTP binding
Biological Process
GO:0007049 cell cycle
GO:0051301 cell division
Cellular Component
GO:0000775 chromosome, centromeric region
GO:0000776 kinetochore
GO:0000777 condensed chromosome kinetochore
GO:0005694 chromosome
GO:0005737 cytoplasm
GO:0005819 spindle
GO:0005856 cytoskeleton
GO:0008021 synaptic vesicle
GO:0030496 midbody
GO:0031105 septin complex
GO:0032154 cleavage furrow
GO:0043679 axon terminus
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000125354
View Gene Order
ENSMUSG00000050379
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa05100
Bacterial invasion of epithelial cells pathway
mmu05100
Bacterial invasion of epithelial cells pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.43053
RefSeq NM_001035430 XM_005227437
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca