Version 5.4
Bos taurus Gene: HOMER2
Summary
InnateDB Gene IDBG-629965.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HOMER2
Gene Name homer protein homolog 2
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000017715
Encoded Proteins
IDBP-681394
homer protein homolog 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000103942:
This gene encodes a member of the homer family of dendritic proteins. Members of this family regulate group 1 metabotrophic glutamate receptor function. The encoded protein is a postsynaptic density scaffolding protein. Alternative splicing results in multiple transcript variants. Two related pseudogenes have been identified on chromosome 14. [provided by RefSeq, Jun 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 21:23577846-23668524
Strand Reverse strand
Band
Transcripts
ENSBTAT00000017648 ENSBTAP00000017648
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.
Predicted by orthology
Total 15 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005515 protein binding
GO:0030160 GKAP/Homer scaffold activity
Biological Process
GO:0008277 regulation of G-protein coupled receptor protein signaling pathway
GO:0035584 calcium-mediated signaling using intracellular calcium source
GO:0048148 behavioral response to cocaine
GO:0048875 chemical homeostasis within a tissue
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0030054 cell junction
GO:0045177 apical part of cell
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000103942
View Gene Order
ENSMUSG00000025813
View Gene Order
Cross-References
SwissProt
TrEMBL Q0VCH1
UniProt Splice Variant
Entrez Gene 510811
UniGene Bt.5922
RefSeq NM_001075467
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC120170 DAAA02052228 DAAA02052229 DAAA02052230
GenPept AAI20171
RNA Seq Atlas 510811

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca