Bos taurus Gene: ITGB8 | |||||||||||
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Summary | |||||||||||
InnateDB Gene | IDBG-630020.3 | ||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
Gene Symbol | ITGB8 | ||||||||||
Gene Name | integrin beta-8 precursor | ||||||||||
Synonyms | |||||||||||
Species | Bos taurus | ||||||||||
Ensembl Gene | ENSBTAG00000003709 | ||||||||||
Encoded Proteins |
integrin, beta 8
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Protein Structure | |||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||
Entrez Gene | |||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000105855:
This gene is a member of the integrin beta chain family and encodes a single-pass type I membrane protein with a VWFA domain and four cysteine-rich repeats. This protein noncovalently binds to an alpha subunit to form a heterodimeric integrin complex. In general, integrin complexes mediate cell-cell and cell-extracellular matrix interactions and this complex plays a role in human airway epithelial proliferation. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||||
Type | Protein coding | ||||||||||
Genomic Location | Chromosome 4:29124581-29216280 | ||||||||||
Strand | Forward strand | ||||||||||
Band | |||||||||||
Transcripts |
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Interactions | |||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Pathway Predictions based on Human Orthology Data | |||||||||||
NETPATH | |||||||||||
REACTOME |
Integrin cell surface interactions pathway
Molecules associated with elastic fibres pathway
Elastic fibre formation pathway
Extracellular matrix organization pathway
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KEGG |
Regulation of actin cytoskeleton pathway
Cell adhesion molecules (CAMs) pathway
ECM-receptor interaction pathway
Focal adhesion pathway
Arrhythmogenic right ventricular cardiomyopathy (ARVC) pathway
Hypertrophic cardiomyopathy (HCM) pathway
Dilated cardiomyopathy pathway
Cell adhesion molecules (CAMs) pathway
ECM-receptor interaction pathway
Regulation of actin cytoskeleton pathway
Focal adhesion pathway
Arrhythmogenic right ventricular cardiomyopathy (ARVC) pathway
Hypertrophic cardiomyopathy (HCM) pathway
Dilated cardiomyopathy pathway
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INOH |
Integrin signaling pathway pathway
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PID NCI |
Integrin family cell surface interactions
Beta5 beta6 beta7 and beta8 integrin cell surface interactions
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Cross-References | |||||||||||
SwissProt | |||||||||||
TrEMBL | F1MVW3 | ||||||||||
UniProt Splice Variant | |||||||||||
Entrez Gene | 536286 | ||||||||||
UniGene | Bt.75176 | ||||||||||
RefSeq | NM_001192875 | ||||||||||
HUGO | |||||||||||
OMIM | |||||||||||
CCDS | |||||||||||
HPRD | |||||||||||
IMGT | |||||||||||
EMBL | DAAA02010141 | ||||||||||
GenPept | |||||||||||
RNA Seq Atlas | 536286 | ||||||||||